Summary
Cultivation ofTrichoderma viride yields the volatile lactone 6-pentyl-alpha-pyrone (6-PP) as principal metabolite in concentration of up to 1 g/l. Separation and enrichment of 6-PP from the culture medium is effected by pervaporation through hydrophobic membranes. Virtually complete removal of 6-PP from inactive culture medium is achieved by batch pervaporation. Unlike steam distillation, pervaporation may be directly coupled to the active fermenter.
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Bengtson, G., Böddeker, K.W., Hanssen, H.P. et al. Recovery of 6-pentyl-alpha-pyrone fromTrichoderma viride culture medium by perevaporation. Biotechnol Tech 6, 23–26 (1992). https://doi.org/10.1007/BF02438682
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DOI: https://doi.org/10.1007/BF02438682