Biotechnology Techniques

, Volume 6, Issue 1, pp 5–8 | Cite as

Reliable on-line monitoring of ammonium ion in a bioreactor

  • Peter Gostomski
  • Henry Bungay


To analyze continuously a stream from a bioreactor for the concentration of ammonium ion, the broth is adjusted to high pH and conveyed to a small mixing chamber containing an ammonia electrode. The system has a delay of only 1 minute and a time constant for response of approximately 1 minute. Fouling and leaching of the electrode membrane are prevented by a small, sealed air gap between the electrode and the sample stream; membrane life is at least five days.


Dilution Rate Sample Stream Variable Speed Drive Flow Rate Effect Ammonia Electrode 
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  1. Hill, F.F., and Thommel, J. (1982). Proc. Biochem. 17(5),16.Google Scholar
  2. Thompson, B.G., Kole, M. and Gerson, D.F. (1985). Biotech. and Bioeng. 27, 818–824.CrossRefGoogle Scholar

Copyright information

© Science & Technology Letters 1992

Authors and Affiliations

  • Peter Gostomski
    • 1
  • Henry Bungay
    • 1
  1. 1.Department of Chemical EngineeringRensselaer Polytechnic InstituteTroy

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