Abstract
δ-Sleep-inducing peptide (1 μg/ml) added to erythrocyte suspension from intact rats enhanced quenching of membrane tryptophanyl fluorescence with pyrene and increased the microviscosity of zones of protein-lipid contacts. Microviscosity and polarity of membrane lipid phase remained unchanged. Exogenous δ-sleep-inducing peptide increased the negative surface charge of the erythrocyte membrane. During cold stress, the efficiency of tryptophane fluorescence quenching with pyrene decreased and microviscosity of protein-lipid contacts decreased, while microviscosity of lipid layer of the erythrocyte membranes did not change; polarity of deep membrane layers and negative surface charge increased. δ-Sleep-inducing peptide normalized the efficiency tryptophane fluorescence quenching with pyrene and membrane microviscosity, polarity, and surface charge.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 9, pp. 317–320, September, 1999
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Shustanova, T.A., Milyutina, N.P., Bondarenko, T.I. et al. Effect of δ-sleep-inducing peptide on rat erythrocyte membrane structure in cold stress. Bull Exp Biol Med 128, 933–935 (1999). https://doi.org/10.1007/BF02438089
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DOI: https://doi.org/10.1007/BF02438089