Abstract
α-Crystallin, an endogenous low-molecular-weight protein with chaperone activity, exerted protective effects on membrane systems of Ca2+ transport into the sarcoplasmic reticulum of skeletal muscles. Protective action of α-crystallin depended on the body state. This effect was not observed in the control and after adaptation to stress, while after stress, especially against the background of adaptation, α-crystallin increased the rate of Ca2+ transport into the sarcoplasmic reticulum and thermal resistance of Ca2+ pump. The mechanisms of α-crystallin activation during stress are discussed.
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N. E. Golantsova and T. G. Sazontova,Byull. Eksp. Biol. Med.,125, No. 1, 40–44 (1998).
T. G. Sazontova,,102, No. 12, 685–687 (1986).
T. G. Sazontova,,108, No. 9, 271–273 (1989).
Yu. V. Arkhipenko, T. G. Sazontova, and C. Rice-Evans,Pathophysiology,4, No. 4, 241–248 (1997).
M. Conconi, I. Petropoulos, I. Emod,et al., Biochem. J.,333, No. 2, 407–415 (1998).
A. Goldberg,Proc. Natl. Acad. Sci. USA,69, No. 9, 2640–2644 (1972).
M. Hermes-Lima and K. Storey,Am. J. Physiol.,265, No. 3, Pt. 2, R646-R652 (1993).
D. Hook and J. Harding,Eur. J. Biochem.,247, No. 1, 380–385 (1997).
D. Hook and J. Harding,Int. J. Biol. Macromol.,22, No. 3-4, 295–306 (1998).
H. Ito, K. Okamoto, and K. Kato,Biochim. Biophys. Acta,1397, No. 2, 223–230 (1998).
F. van den Klundert, M. Gijsen, P. van den Jssel,et al., Eur. J. Cell. Biol.,75, No. 1, 38–45 (1998).
J. Lee, T. Samejima, J. Liao,et al., Biochem. Biophys. Res. Commun.,244, No. 2, 379–383 (1998).
J. Lee, T. Satoh, H. Shinoda,et al.,,237, No. 2, 277–282 (1997).
S. Longoni, S. Lattonen, G. Bullock, and M. Chiesi,Moll. Cell. Biochem.,97, 121–128 (1990).
F. Z. Meerson, T. G. Sazontova, and Yu. V. Arkhipenko,Biomed. Sci.,1, No. 4, 373–378 (1990).
P. Mehlen, X. Preville, P. Chareyron,et al., J. Immunol.,154, No. 1, 363–374 (1995).
J. Pal, S. Bera, and S. Ghosh,Ophthalmic Res.,30, No. 5, 271–279 (1998).
K. Rajaraman, B. Raman, T. Ramakrishna, and C. Rao,Biochem. Biophys. Res. Commun.,249, No. 3, 917–921 (1998).
W. Siems, F. van Kuijk, R. Maass, and R. Brenke,Free Radic. Biol. Med.,16, 299–305 (1994).
M. Spasic, Z. Saicic, B. Buzadzic,et al.,,15, 291–299 (1993).
K. Wang and A. Spector,Invest. Ophthalmol. Vis. Sci.,36, No. 2, 311–321 (1995).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 9, pp. 279–282, September, 1999
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Sazontova, T.G., Matskevich, A.A., Babizhaev, M.A. et al. Chaperone activity of α-crystallin in relation to the sarcoplasmic reticulum Ca2+ pump of skeletal muscles in stress and adaptation. Bull Exp Biol Med 128, 899–902 (1999). https://doi.org/10.1007/BF02438079
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DOI: https://doi.org/10.1007/BF02438079