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Ultrastructural reorganization of adrenal cortex in rats exposed to hypoxia and treated with nandrolone

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Single and repeated hypoxic exposures induced different ultrastructural changes of varying intensity in adrenocorticocytes of rat adrenal zona fasciculata and zona reticularis. Destructive changes in cells were caused by the antianabolic effect of hypoxia and inhibition of regeneration and plastic processes. Treatment with nandrolone (Nerobolil, Gedeon Richter) diminished this effect and stimulated secretory activity of adrenocorticocytes.

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Authors and Affiliations

  1. Laboratory of Pathophysiology and Functional Morphology, Laboratory of Histocytometry and Stereology, Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk

    E. V. Koldysheva, E. L. Lushnikova & I. S. Proskuryakova

Authors
  1. E. V. Koldysheva
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  2. E. L. Lushnikova
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  3. I. S. Proskuryakova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 5, pp. 588–592, May, 1999

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Koldysheva, E.V., Lushnikova, E.L. & Proskuryakova, I.S. Ultrastructural reorganization of adrenal cortex in rats exposed to hypoxia and treated with nandrolone. Bull Exp Biol Med 127, 535–539 (1999). https://doi.org/10.1007/BF02434961

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  • DOI: https://doi.org/10.1007/BF02434961

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