Abstract
The concentration of albumin and the state of its binding centers in the serum and abdominal exudate from patients with acute pancreatitis were evaluated using a fluorescent technique. The total albumin concentration was below normal by 33%. The ratio of effective to total concentration also decreased attesting to conformational changes in the albumin molecule. Albumin molecules are released into exudate in its native form, but sometimes albumin in the exudate is dramatically changed probably due to bursa omentalis seal failure and its concentration sharply decreased probably due to proteolytic degradation.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 12, pp. 660–662, December, 1999
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Rodoman, G.V., Shalaeva, T.I., Dobretsov, G.E. et al. Albumin concentration and properties in the blood and exudate in acute pancreatitis. Bull Exp Biol Med 128, 1232–1234 (1999). https://doi.org/10.1007/BF02434826
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DOI: https://doi.org/10.1007/BF02434826