Bulletin of Experimental Biology and Medicine

, Volume 129, Issue 2, pp 193–195 | Cite as

Immunohistochemical location of major histocompatibility complex class 1 antigens in human placenta

  • Yu. V. Gladyshev
  • S. I. Kolesnikov
  • S. V. Alisievich
Morphology and Pathomorphology


Distribution of major histocompatibility complex class I antigens in the postpartum human placenta was studied by immunohistochemical method. Positive staining was observed in endotheliocyte cytoplasm in vessels of chorionic villi. The surface of trophoblast, cytotrophoblast, and connective tissue cells did not stain. These data indicate a peculiar «masking» of antigens essential for normal course of gestation.

Key Words

placenta major histocompatibility complex antigens 


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Copyright information

© Kluwer Academic/Plenum Publishers 2000

Authors and Affiliations

  • Yu. V. Gladyshev
    • 1
  • S. I. Kolesnikov
    • 1
  • S. V. Alisievich
    • 1
  1. 1.Research Center of Medical Ecology, Research Center of Reconstructive and Repair Surgery, East Siberian Research CenterSiberian Division of Russian Academy of Medical SciencesIrkutsk

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