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Experimental validation of efficiency of probiotics in combined therapy of destructive pancreatitis

Abstract

the mechanism ofE. coli translocation after its intragastral administration was studied in rats with acute pancreatitis. Bacterial dissemination into visceral organs was shown. Therapy with probiotic sporobacterin was more effective than antibiotic (cefaxon) therapy. Contamination of the viscera with Escherichia was notably decreased.

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References

  1. L. N. Zhinkin,Radioactive Indicators in Histology [in Russian], Leningrad (1959), pp. 5–33.

  2. Yu. T. Kadoshchuk and A. A. Plokhoi,Vestn. Khir., No. 7-8, 123–126 (1991).

    Google Scholar 

  3. V. S. Mayat, G. A. Buromskaya, Yu. P. Atanov, and V. V. Laptev,Khirurgiva, No. 10, 23–28 (1978).

    Google Scholar 

  4. V. I. Nikitenko, ——Ibid., No. 9, 94–98 (1990).

    Google Scholar 

  5. V. I. Nikitenko,Diagnosis, Treatment, and Prevention of Pyoinflammatory Complications in Traumatological and Orthopedic Patients, Abstract of Doct. Med. Sci. Dissertation, Moscow (1985), p. 20.

  6. V. S. Savel'ev and V. A. Kubyshkin,Khirurgiya, No. 6, 22–28 (1993).

    Google Scholar 

  7. V. I. Filin and A. P. Kostyuchenko,Urgent Pancreatology [in Russian], St. Petersburg (1994).

  8. R. D. Berg,Scientific Basis of the Probiotic Concept, ed. R. Fuller, London (1992), pp. 55–85.

  9. L. Gianotti, M. Braga, and J. W. Alexander,Chir. Ital.,47, No. 2, 14–24 (1995).

    PubMed  CAS  Google Scholar 

  10. R. Rao, R. A. Prinz, G. B. Kazantsev,et al., Surgery,119, No. 6, 657–663 (1996).

    PubMed  CAS  Article  Google Scholar 

  11. E. Tarpila, P. O. Nistrom, L. Franzen, and I. Ihse,Engl. J. Surg.,159, No. 2, 109–113 (1993).

    CAS  Google Scholar 

  12. A. L. Widdison, N. D. Karanjia, C. Alvares, and H. A. Reber,Am. J. Surg. 163, No. 1, 100–103 (1992).

    PubMed  CAS  Article  Google Scholar 

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 2, pp. 204–207, February, 2000

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Tarasenko, V.S., Stadnikov, A.A., Nikitenko, V.I. et al. Experimental validation of efficiency of probiotics in combined therapy of destructive pancreatitis. Bull Exp Biol Med 129, 176–178 (2000). https://doi.org/10.1007/BF02434804

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  • DOI: https://doi.org/10.1007/BF02434804

Key Words

  • acute pancreatitis
  • translocation
  • probiotics