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Experimental validation of efficiency of probiotics in combined therapy of destructive pancreatitis


the mechanism ofE. coli translocation after its intragastral administration was studied in rats with acute pancreatitis. Bacterial dissemination into visceral organs was shown. Therapy with probiotic sporobacterin was more effective than antibiotic (cefaxon) therapy. Contamination of the viscera with Escherichia was notably decreased.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 2, pp. 204–207, February, 2000

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Tarasenko, V.S., Stadnikov, A.A., Nikitenko, V.I. et al. Experimental validation of efficiency of probiotics in combined therapy of destructive pancreatitis. Bull Exp Biol Med 129, 176–178 (2000).

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Key Words

  • acute pancreatitis
  • translocation
  • probiotics