Immunological characteristics of skin preparations
- 21 Downloads
Effects of three preparations from porcine skin on the number of antibody-producing mouse splenocytes at the peak of primary immune response and on the restoration of the sensitivity of background rosette-forming splenocytes to inhibitory effect of azathioprine were studied in thymectomized mice. All three preparations were active in the first test, while in the second test only the preparation with molecular weight below 1.4 kD was active. The effects of preparations on B and T immunity have been demonstrated.
Key Wordsimmunomodulators cytokins skin B immunity T immunity
Unable to display preview. Download preview PDF.
- 1.V. Ya. Arion, O. V. Belova, V. F. Orlova,et al., Byull. Izobret., No. 18, 24 (1995).Google Scholar
- 2.O. V. Belova, V. Ya. Arion, Yu. M. Lopukhin,et al., Rus. J. Immunol.,4, No. 2, 151–157 (1999).Google Scholar
- 3.E. Ziegl and E. Bem,Immunological Methods [in Russian], Moscow (1979), pp. 96–107.Google Scholar
- 4.I. V. Zimina, Yu. M. Lopukhin, and V. Ya. Arion,Immunologiya, No. 1, 8–13 (1994).Google Scholar
- 5.Yu. M. Lopukhin, V. Ya. Arion, V. F. Ivanova,et al., Byull. Eksp. Biol. Med.,114, No. 11, 473–475 (1992).Google Scholar
- 6.R. L. Edel'son and D. M. Fink,V Mire Nauki, No. 8, 16–24 (1985).Google Scholar
- 8.M. Dardenne and J.-F. Bach,Biological Activity of Thymic Hormones, Eds. V. Bekkum and D. W. Rotterdam, New York (1975), pp. 235–243.Google Scholar
- 9.A. C. Gornall, C. J. Bardawill, and M. M. David,J. Biol. Chem.,177, 751–766 (1949).Google Scholar
- 13.G. Schmidt and S. J. Tannhauser,J. Biol. Chem.,161, 83–89 (1945).Google Scholar