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Bulletin of Experimental Biology and Medicine

, Volume 129, Issue 2, pp 168–170 | Cite as

Immunological characteristics of skin preparations

  • V. Ya. Arion
  • O. V. Belova
  • T. A. Lukanidina
  • O. B. Sysoeva
  • V. V. Dvortsova
  • Yu. N. Breusov
Microbiology and Immunology

Abstract

Effects of three preparations from porcine skin on the number of antibody-producing mouse splenocytes at the peak of primary immune response and on the restoration of the sensitivity of background rosette-forming splenocytes to inhibitory effect of azathioprine were studied in thymectomized mice. All three preparations were active in the first test, while in the second test only the preparation with molecular weight below 1.4 kD was active. The effects of preparations on B and T immunity have been demonstrated.

Key Words

immunomodulators cytokins skin B immunity T immunity 

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Copyright information

© Kluwer Academic/Plenum Publishers 2000

Authors and Affiliations

  • V. Ya. Arion
    • 1
  • O. V. Belova
    • 1
  • T. A. Lukanidina
    • 1
  • O. B. Sysoeva
    • 1
  • V. V. Dvortsova
    • 1
  • Yu. N. Breusov
    • 1
  1. 1.Laboratory of Molecular Immunology, Institute of Physicochemical MedicineMinistry of Health of the Russian FederationMoscow

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