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Surface activity of phosphatidylcholines as the basis for surfactant replacement therapy

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Using the methods of surface balance we compared the effects of different phosphatidylcholines and synthetic surfactant Exosurf on the equilibrium surface tension at the air-water interface. It was found that dipalmitoyl-lecithin, the principal component of natural surfactant, and its synthetic substitutes can be replaced by other phosphatidylcholines, in particular, by modified soybean phosphatidylcholine phospholipon. It was demonstrated that equilibrium surface tension is an informative characteristic in the assessment of potential components for synthetic surfactants.

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Correspondence to T. S. Zakharova.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 2, pp. 168–170, February, 2000

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Zakharova, T.S., Fortinskaya, E.S., Kochetova, M.M. et al. Surface activity of phosphatidylcholines as the basis for surfactant replacement therapy. Bull Exp Biol Med 129, 144–145 (2000). https://doi.org/10.1007/BF02434793

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  • DOI: https://doi.org/10.1007/BF02434793

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