Abstract
Alcohol intoxication aggravated by exposure to ecologically unfavorable factors (methanol and furfural vapors) induced pronounced desynchronization of hematologic processes, dramatic disturbance of carbohydrate metabolism, and considerable structural changes in internal organs. Treatment with glutamic acid reduced pathological manifestations and increased the adaptive capacities of the organism. Functional and morphological changes observed in laboratory animals after treatment with the neurometabolic compound glutamic acid could be classified as reversible.
Similar content being viewed by others
References
Yu. V. Burov, S. E. Metkalova, and L. E. Davydova,Vopr. Narkol., No. 4, 50–56 (1994).
I. A. Kassirskii and G. A. Alekseev,Clinical Hematology [in Russian], Moscow (1970).
G. I. Krasovskii and O. R. Sobinyakova,Gigiena i Sanitariya, No. 4, 29–34 (1970).
E. N. Mosyagina,Erythrocyte Balance in Norm and Pathology [in Russian], Moscow (1962).
A. G. Solov'ev, G. N. Degteva, and P. I. Sidorov,Byull. Eksp. Biol. Med.,96, No. 8, 195–197 (1983).
A. M. Khokha,Uspekhi Sovrem. Biol., No. 5, 573–580 (1994).
M. Hardman, P. Jeyarathar, and K. Hitson,Alcohol Clin. Exp. Res., No. 2, 212 (1994).
C. Lang, P. Molina, and N. Skrepnick,Am. J. Physiol., No. 6, 863–869 (1994).
Z. Spolarics, G. Bagly, and P. Pekala,Ibid.,, No. 6, 886–891 (1994).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 129, No. 3, pp. 321–325, March, 2000
Rights and permissions
About this article
Cite this article
Sidorov, P.I., Gromova, L.E., Solov'ev, A.G. et al. Glutamic acid in treatment of alcohol intoxication aggravated by ecologically unfavorable factors. Bull Exp Biol Med 129, 275–278 (2000). https://doi.org/10.1007/BF02433905
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02433905