Bulletin of Experimental Biology and Medicine

, Volume 129, Issue 1, pp 14–18 | Cite as

Formation of SiO2-induced granulomas in mice of various strains

  • Ya. Sh. Shvarts
  • A. A. Zubakhin
  • A. S. Ustinov
  • M. I. Dushkin
  • Yu. I. Ragino
General Pathology and Pathophysiology
  • 19 Downloads

Abstract

Peculiarities of SiO2-induced granulomas in the liver and subcutaneous fat were studied in C57B1/6, CBA/Lac, BALB/c, C57BR, and C3H/F mice. Infiltrative and fibrogenic responses were interrelated and strain-specific primarily due to various intensities of myelopoiesis.

Key words

mouse strains granulomas macrophages SiO2 

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References

  1. 1.
    G. P. Brown, M. Monick, and G. W. Hunninghake,Am. Rev. Respir. Dis.,138, No. 1, 85–89 (1988).PubMedGoogle Scholar
  2. 2.
    A. H. Callis, P. G. Sohnle, G. S. Mandel,et al., J. Lab. Clin. Med.,105, No. 5, 547–553 (1985).PubMedGoogle Scholar
  3. 3.
    M. Hirata, M. Kage, M. Takushima, and T. J. Fukuma,Parasitology,79, No. 2, 266–273 (1993).CrossRefGoogle Scholar
  4. 4.
    C. J. Johnston, B. Piedboeuf, R. Baggs,et al., Radiat. Res.,142, No. 2, 197–203 (1995).PubMedGoogle Scholar
  5. 5.
    F. Y. Liew, Y. Li, D. Moss,et al., Eur. J. Immunol.,21, 3009–3014 (1991).PubMedGoogle Scholar
  6. 6.
    De L. Lopez and M. Rojkind,J. Histochem. Cytochem.,33, No. 8, 737–743 (1985).Google Scholar
  7. 7.
    M. Lovik and O. Closs,Clin. Exp. Immunol.,75, 461–465 (1989).PubMedGoogle Scholar
  8. 8.
    P. F. Piguet, M. A. Collart, G. E. Grau,et al., Nature,344, No. 6263, 245–247 (1990).PubMedCrossRefGoogle Scholar
  9. 9.
    C. Sunderkotter, M. Kunz, K. Steinbrink,et al., J. Immunol.,151, No. 9, 4891–4901 (1993).PubMedGoogle Scholar
  10. 10.
    K. Takahashi, M. Naito, S. Umeda, and L. D. Shultz,Am. J. Pathol.,144, No. 6, 1381–1392 (1994).PubMedGoogle Scholar
  11. 11.
    M. Tsuji, V. B. Dimov, and T. Yoshida,,147, No. 4, 1001–1015 (1995).PubMedGoogle Scholar
  12. 12.
    E. R. Weiberm,Practical Methods for Biological Morphometry, Ed. E. R. Weibel, London (1979), Vol. 1, p. 26.Google Scholar
  13. 13.
    A. O. Williams and A. D. Knapton,Hepatology,23, 1268–1275 (1996).PubMedGoogle Scholar
  14. 14.
    Z. Xing, Y. Ohkawara, M. Jordana,et al., J. Clin. Invest.,97, No. 4, 1102–1110 (1996).PubMedCrossRefGoogle Scholar
  15. 15.
    A. Yoshida, Y. Koide, M. Uchijima, and T. O. Yoshida,J. Immunol.,155, 2057–2066 (1995).PubMedGoogle Scholar

Copyright information

© Kluwer Academic/Plenum Publishers 2000

Authors and Affiliations

  • Ya. Sh. Shvarts
    • 1
  • A. A. Zubakhin
    • 1
  • A. S. Ustinov
    • 1
  • M. I. Dushkin
    • 1
  • Yu. I. Ragino
    • 1
  1. 1.Siberian Division of the Russian Academy of Medical SciencesInstitute of TherapyNovosibirsk

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