Skip to main content
SpringerLink
Log in

Erythrocyte membranes in patients with malignant tumors as shown by fluorescent probing

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Erythrocyte membranes were examined by fluorescent probing in untreated patients with tumors of different localization (lung cancer, head and neck tumors, stomach and colorectal cancer). Tumor growth was associated with pronounced disorders in erythrocyte membranes: increased viscosity of the lipid bilayer, including protein-lipid contacts, and modification membrane surface layers. The degree of changes in the studied parameters depended on the tumor location.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. A. A. Boldyrev,Membrane Biochemistry [in Russian], Moscow (1986).

  2. Yu. A. Vladimirov and G.E. Dobretsov,Fluorescent Probes in investigation of Biological Membranes [in Russian], Moscow (1980).

  3. I. A. Gribova and V. V. Sololov,Problems in Predisease and Early Stages of Occupational Diseases [in Russian], Moscow (1980), pp. 67–76.

  4. A. I. Deev, Yu. G. Osis, V. E. Formazyuk,et al., Biofizika,28, No. 4, 629–631 (1983).

    PubMed  CAS  Google Scholar 

  5. G. E. Dobretsov,Fluorescent Probes in Analysis of Cells. Membranes, and Lipoproteins [in Russian], Moscow (1989).

  6. V. N. Zharov, I. K. Filipov, M. I. Bakanov, and I. V. Koshel',Byull. Eksp. Biol. Med.,117, No. 1, 29–32 (1994).

    Article  Google Scholar 

  7. G. I. Kozinets and E. D. Gol'dberg,Kinetic Aspects of Hemopoiesis [in Russian], Tomsk (1982).

  8. E. V. Kozycheva and E. A. Endakova,Byull. Sib. Otdelen. Ross. Akad. Med. Nauk, No. 1, 18–23 (1998).

    Google Scholar 

  9. V. V. Novitskii, E. A. Stepovaya, N. G. Bazhenova,et al., Byull. Eksp. Biol. Med.,126, No. 8, 204–206 (1998).

    CAS  Google Scholar 

  10. M. P. Petrova, T. A. Serbinova, and P. S. Vasil'ev,Lab. Delo, No. 8, 503 (1978).

    PubMed  Google Scholar 

  11. V. D. Prokop'eva,The Role of Different Sites of Membrane in Modifying Effect of ATP on Ca-ATPase in Sarcoplasmatic Reticulum, Abstract of Cand. Biol. Sci. Dissertation, Moscow (1982).

  12. B. S. Khyshiktuev, N. A. Khyshiktueva, V. N. Ivanov,et al., Vopr. Onkol.,39, No. 7-12, 288–291 (1993).

    PubMed  CAS  Google Scholar 

  13. J. T. Dodge, C. Mitchell, D. J. Hanahan,et al., Arch. Biochem. Biophys.,100, No. 1, 119–130 (1963).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk

    V. V. Novitskii, E. A. Stepovaya, A. V. Batukhtin, V. E. Gol'dberg & M. V. Kolosova

  2. Institute of Oncology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk

    V. V. Novitskii, E. A. Stepovaya, A. V. Batukhtin, V. E. Gol'dberg & M. V. Kolosova

  3. Siberian State Medical University, Tomsk

    V. V. Novitskii, E. A. Stepovaya, A. V. Batukhtin, V. E. Gol'dberg & M. V. Kolosova

Authors
  1. V. V. Novitskii
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. A. Stepovaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. V. Batukhtin
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. V. E. Gol'dberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. V. Kolosova
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated fromByullenten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 8, pp. 226–229, August, 1999

Rights and permissions

Reprints and permissions

About this article

Cite this article

Novitskii, V.V., Stepovaya, E.A., Batukhtin, A.V. et al. Erythrocyte membranes in patients with malignant tumors as shown by fluorescent probing. Bull Exp Biol Med 128, 857–859 (1999). https://doi.org/10.1007/BF02433834

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02433834

Key Words

Search

Navigation