Adrenergic regulation of lymphocyte proliferative response in cultures with T-cell mitogens
- 20 Downloads
The effects of epinephrine, β-adrenergic agonist terbutaline sulfate, and cAMP phosphodiesterase inhibitor theophylline on proliferative response of peripheral blood lymphocytes from healthy subjects were studied in cultures with phytohemagglutinin and concanavalin A. Both adrenergic agonists inhibited lymphocyte blastogenesis, but the effect of epinephrine was more pronounced.
Key Wordsepinephrine β-adrenergic compounds lymphocyte blastogenesis
Unable to display preview. Download preview PDF.
- 1.Yu. N. Tyurin and A. A. Makarov,Computer Processing of Data [in Russian], Moscow (1995).Google Scholar
- 2.A. A. Yarilin,Cell Factors of Immunogenesis Regulation [in Russian], Novosibirsk (1985), pp. 24–39.Google Scholar
- 5.B. Kurz, J. Feindt, B. VonGaudecker, et al.,Brit. J. Pharmacol.,120, No. 8, 1401–1408 (1997).Google Scholar
- 10.A. D. Strosberg,Obes. Res.,3, Suppl. 4, 501–505 (1995).Google Scholar