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Vascular thrombogenicity and thromboresistance during postischemic reperfusion

  • General Pathology and Pathologigal Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Responsiveness, thrombogenicity, and thromboresistance of mesenteric microvessels were studied in rats during postischemic reperfusion of the intestine, brain, and hind limb. Irrespective to localization of the ischemized organ, the mesenteric microvessels increased responsiveness and decreased thromboresistance. Vascular thrombogenicity depended on the localization of ischemia. During cerebral reperfusion, thrombogenicity of some venules was decreased against the background of its general increase in arterioles. Microvascular disturbances and predominantly related to perturbations in nitric oxide synthesis.

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Authors and Affiliations

  1. Department of Pathophysiology, I. P. Pavlov State Medical University, St. Petersburg

    T. D. Vlasov

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  1. T. D. Vlasov
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 8, pp. 168–171, August, 1999

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Vlasov, T.D. Vascular thrombogenicity and thromboresistance during postischemic reperfusion. Bull Exp Biol Med 128, 803–805 (1999). https://doi.org/10.1007/BF02433820

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  • DOI: https://doi.org/10.1007/BF02433820

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