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Analysis of bromantane pharmacological spectrum


Bromantane (2[n-bromphenyl]aminoadamantane) in doses of 40–60 mg/kg had no effect on spontaneous motor activity of BALB/c mice in a Optovarimex apparatus and prevented freezing in the open field test, but stimulated motor activity in C57B1/6 mice. It is concluded that psychostimulatory and anxiolytic effects are present in the spectrum of the pharmacological activity of bromantane.

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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 11, pp. 529–531, November, 1999

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Seredenin, S.B., Miramedova, A.G. Analysis of bromantane pharmacological spectrum. Bull Exp Biol Med 128, 1116–1118 (1999).

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Key words

  • bromantane
  • inbred mice
  • anxiolytic