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Analysis of bromantane pharmacological spectrum

  • Pharmacology and Toxicology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Bromantane (2[n-bromphenyl]aminoadamantane) in doses of 40–60 mg/kg had no effect on spontaneous motor activity of BALB/c mice in a Optovarimex apparatus and prevented freezing in the open field test, but stimulated motor activity in C57B1/6 mice. It is concluded that psychostimulatory and anxiolytic effects are present in the spectrum of the pharmacological activity of bromantane.

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Authors and Affiliations

  1. Laboratory of Pharmacogenetics, Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow

    S. B. Seredenin & A. G. Miramedova

Authors
  1. S. B. Seredenin
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  2. A. G. Miramedova
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 11, pp. 529–531, November, 1999

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Seredenin, S.B., Miramedova, A.G. Analysis of bromantane pharmacological spectrum. Bull Exp Biol Med 128, 1116–1118 (1999). https://doi.org/10.1007/BF02433415

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  • DOI: https://doi.org/10.1007/BF02433415

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