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Bulletin of Experimental Biology and Medicine

, Volume 127, Issue 2, pp 200–202 | Cite as

Prevention of experimental pseudotuberculosis infection by immunization with porin fromYersinia pseudotuberculosis

  • I. V. Darmov
  • I. V. Marakulin
  • I. P. Pogorel'skii
  • O. D. Novikova
  • O. Yu. Portnyagina
  • T. F. Solov'eva
Microbiology and Immunology

Abstract

Protective properties of two molecular forms of porin, a protein from the outer membrane ofYersinia pseudotuberculosis, are studied in animals infected with pseudotuberculosis and plague agents. The effect of adjuvant on the protective activity of porin is investigated. The possibility of using porin as a component of chemical antipseudotuberculosis vaccine is demonstrated.

Key Words

porin protective activity pseudotuberculosis 

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Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • I. V. Darmov
    • 1
  • I. V. Marakulin
    • 1
  • I. P. Pogorel'skii
    • 1
  • O. D. Novikova
    • 2
  • O. Yu. Portnyagina
    • 2
  • T. F. Solov'eva
    • 2
  1. 1.Institute of MicrobiologyMinistry of Defense of Russian FederationKirov
  2. 2.Pacific Institute of Bioorganic ChemistryFar-Eastem Division of the Russian Academy of SciencesVladivostok

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