, Volume 9, Issue 2, pp 41–45 | Cite as

Effect of antioxidants on rotifer lifespan and activity

  • Vera Bozovic
  • Hildegard E. Enesco


The antioxidant thiazolidine-4-carboxylic acid (TCA) is a sulfhydryl radical scavenger. At concentrations of 400 or 800 uM it was found to significantly extend the mean lifespan of the rotifer Asplanchna brighwelli by 7.8%. Maximum lifespan of A. brighwelli was not influenced by this drug. Butylated hydroxytoluene (BHT), a true chain-breaking antioxidant, was toxic to the rotifers. Vitamin C, an antioxidant of the reducing agent category, had no effect on rotifer lifespan. Although TCA brought about a significant increase in mean rotifer lifespan, it did not significantly affect the activity level of the rotifers. The results presented here are consistent with the free radical theory of aging.


Butylate Radical Theory Sulfhydryl Butylate Hydroxytoluene Hydroxytoluene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© American Aging Association, Inc. 1986

Authors and Affiliations

  • Vera Bozovic
    • 1
  • Hildegard E. Enesco
    • 1
  1. 1.Department of BiologyConcordia UniversityMontrealCanada

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