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Diet and life extension in animal model systems

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Abstract

Recent studies have shown that beneficial effects can be brought about when underfeeding is initiated in adult as well as young growing animals. In addition, such dietary manipulations have been shown to delay the onset of a variety of diseases although its relationship to total incidence has not been established. It has been proposed that dietary restriction reduces protein synthesis and increases lifespan by retarding genetic informational transfer during early life and reducing the use of the genetic code and thereby minimizing genetic imperfections as they may occur during late life.

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Author information

Authors and Affiliations

  1. Section on Comparative Nutrition, Gerontology Research Center, National Institute on Aging, Baltimore City Hospitals, Baltimore, Maryland, 21224

    Charles H. Barrows Jr. & Gertrude C. Kokkonen

  2. National Institutes of Health, Baltimore City Hospitals, Baltimore, Maryland, 21224

    Charles H. Barrows Jr. & Gertrude C. Kokkonen

Authors
  1. Charles H. Barrows Jr.
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  2. Gertrude C. Kokkonen
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Additional information

This is the first paper of the mini-symposium on nutrition and aging organized by Charles H. Barrows, Jr., and presented on Thursday, September 29, 1977 as part of the 7th Annual Meeting of the American Aging Association in New York City.

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Barrows, C.H., Kokkonen, G.C. Diet and life extension in animal model systems. AGE 1, 131–143 (1978). https://doi.org/10.1007/BF02432187

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  • DOI: https://doi.org/10.1007/BF02432187

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