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Levodopa prevents mammary lipomas in rats

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Abstract

High Concentrations of the dopaminergic drug levodopa (L-dopa, L-3, 4-dihydroxyphenylalanine) administered to female rats in their food prevented the occurrence of mammary lipomas or recurrence of tumors after surgical removal. The mean life span was prolonged by L-dopa alone and to a slightly greater degree by L-dopa plus surgical removal of tumors.

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Author notes

  1. M. C. McNamara

    Present address: Department of Psychology, Miami University, Oxford, Ohio, 45056

Authors and Affiliations

  1. Department of Physiology, University of North Carolina, School of Medicine, Chapel Hill, North Carolina, 27514

    M. C. McNamara & A. T. Miller Jr.

  2. Dental Research Center, University of North Carolina, School of Dentistry, Chapel Hill, North Carolina, 27514

    G. B. Libby Jr.

Authors
  1. M. C. McNamara
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  2. A. T. Miller Jr.
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  3. G. B. Libby Jr.
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McNamara, M.C., Miller, A.T. & Libby, G.B. Levodopa prevents mammary lipomas in rats. AGE 1, 83–84 (1978). https://doi.org/10.1007/BF02432102

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  • DOI: https://doi.org/10.1007/BF02432102

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