AGE

, Volume 4, Issue 3, pp 85–87 | Cite as

Effect of age and alcohol consumption on plasma lipids in the rat

  • Steven R. Gambert
  • Joseph J. Barboriak
Article

Abstract

Rats aged 6 weeks (young), 6 months (mature), and 20 months (senescent) were offered alcohol ad libitum for 3 weeks to study the interrelationship between alcohol, age, and serum lipids. Although the total quantity of alcohol consumption increased with age, senescent rats actually consumed less alcohol per gram body weight per day as compared to either mature or young rats. Increasing age alone was associated with higher levels of total serum cholesterol and high-density lipoprotein cholesterol. Triglyceride levels were not affected by age. Alcohol consumption elevated high density lipoprotein cholesterol in young rats, however, did not alter this lipid fraction in either mature or senescent rats. Triglyceride levels were elevated by alcohol only in senescent rats.

Keywords

Lipid Alcohol Cholesterol Alcohol Consumption High Density Lipoprotein 

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Copyright information

© American Aging Association, Inc. 1981

Authors and Affiliations

  • Steven R. Gambert
    • 1
    • 2
  • Joseph J. Barboriak
    • 1
    • 2
  1. 1.Department of Medicine and PharmacologyThe Medical College of WisconsinMilwaukee (Wood)
  2. 2.Department of MedicineVeterans Administration Medical CenterMilwaukee (Wood)

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