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AGE

, Volume 8, Issue 4, pp 128–135 | Cite as

Effect of sulfur-containing compounds on the life span of Drosophila

  • Harold R. Massie
  • Trevor Williams
Article

Abstract

Dietary supplements of glutathione, glutathione precursors and other sulfur-containing molecules were fed to Drosophila. Marginal increases in life span were found for 0.078M pyroglutamic acid (+ 9.1%), 0.01M L-methionine (+ 4.9%), and 0.01M methionine + 1 mg/ml vitamin E (+ 7.3%). 0.05M L-methionine plus 10% casein increased life span by 14.8%. For all other concentrations of the following compounds life span was either unchanged or decreased: N-acetyl-L-cysteine, casein, cysteine, glutamic acid, glutathione, glycine, L-methionine, DL-methionine, DL-methionine sulfone, DL-methionine-DL-sulfoxide, L-pyroglutamic acid (5-oxoproline), sodium bisulfite, thiazolidine, 3,3′-thiodipropionic acid and thioproline (thiazolidine carboxylic acid).

Keywords

Life Span Bisulfite Thiazolidine Sodium Bisulfite Pyroglutamic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© American Aging Association, Inc. 1985

Authors and Affiliations

  • Harold R. Massie
    • 1
  • Trevor Williams
    • 1
  1. 1.Masonic Medical Research LaboratoryUtica

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