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Desquamative interstitial pneumonitis and alveolar lipoproteinosis: Diagnostic difficulties and therapy problems with an infant

Abstract

A desquamative, interstitial pneumonitis was diagnosed histologically in a 9-month-old boy who first became ill at the age of 5 weeks. The desquamative interstitial pneumonitis was associated with an acquired cytomegalovirus (CMV) infection. Despite treatment with corticoids, acyclovir and artificial ventilation, the patient died of pulmonary insufficiency at the age of 15 months. The autopsy revealed an alveolar lipoproteinosis.

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Abbreviations

DIP:

desquamative interstitial pneumonitis

UIP:

usual interstitial pneumonitis

ALP:

alveolar lipoproteinosis

CFR:

Complement fixing reaction

CMV:

cytomegalovirus infection

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Correspondence to K. Schneider.

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Schneider, K., Brünstler, I., Vogel, H. et al. Desquamative interstitial pneumonitis and alveolar lipoproteinosis: Diagnostic difficulties and therapy problems with an infant. Eur J Pediatr 145, 575–578 (1986). https://doi.org/10.1007/BF02429072

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Key words

  • Desquamative interstitial pneumonitis
  • Alveolar lipoproteinosis
  • Cytomegalovirus disease