A desquamative, interstitial pneumonitis was diagnosed histologically in a 9-month-old boy who first became ill at the age of 5 weeks. The desquamative interstitial pneumonitis was associated with an acquired cytomegalovirus (CMV) infection. Despite treatment with corticoids, acyclovir and artificial ventilation, the patient died of pulmonary insufficiency at the age of 15 months. The autopsy revealed an alveolar lipoproteinosis.
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desquamative interstitial pneumonitis
usual interstitial pneumonitis
Complement fixing reaction
Bhagwat AG, Wentworth P, Conen PE (1970) Observation on the relationship of desquamative interstitial pneumonia and pulmonary alveolar proteinosis in childhood: a pathologic and experimental study. Chest 58:326
Carrington CB, Gaensler EA, Coutu RE, FitzGerald MX, Gupta RG (1978) Natural history and treated course of usual and desquamative interstitial pneumonia. N Engl J Med 298:801–809
Colon AR, Lawrence RD, Mills SD, O'Connell EJ (1971) Childhood pulmonary alveolar proteinosis. Am J Dis Child 121:481–485
Gaensler EA, Goff AM, Prowse CM (1966) Desquamative interstitial pneumonia N Engl J Med 274:113–128
Heitzman ER (1984) Chronic interstitial pneumonia. In: Heitzman ER (ed) The Lung: radiologic-pathologic correlations. CV Mosby Co, St Louis, pp 237–249
Hewitt CJ, Hull D, Keeling JW (1977) Fibrosing alveolitis in infancy and childhood. Arch Dis Child 52:22–37
Katzenstein AL, Ashin FB (1982) Pulmonary alveolar proteinosis. In: Katzenstein AL (ed) Surgical pathology of nonneoplastic lung disease. WB Saunders Co, Philadelphia, pp 347–349
Liebow AA, Steer A, Billingsley JG (1965) Desquamative interstitial pneumonia. Am J Med 39:369–404
McCook TA, Kirks DR, Merten DF, Osborne DR, Spock A, Pratt PC (1981) Pulmonary alveolar proteinosis in children. Am J Roentgenol 137:1023–1027
Patechefsky AS, Israel LH, Hoch WS, Gordon G (1973) Desquamative interstitial pneumonia: relationship to interstitial fibrosis. Thorax 28:680–693
Riley HD (1983) Pulmonary alveolar proteinosis. In: Kendig EL, Chernick V (eds) Disorders of the respiratory tract in children. Saunders, Philadelphia, pp 424–427
Rosen SH, Castelman B, Liebow AA (1958) Pulmonary alveolar proteinosis. N Engl J Med 258:1123
Schäfer H, Burkhardt A (1983) Stoffwechselstörungen der Lunge. In: Doerr W, Seifert G, Uehlinger E (eds) Handbuch der Speziellen Pathologischen Anatomie. Springer-Verlag, Berlin, pp 998–1003
Smith SD, Cho CT, Brahmacupta N, Lenahan MF (1977) Pulmonary involvement with cytomegalovirus infections in children. Arch Dis Child 52:441–446
Whitley RJ, Brasfield D, Reynolds DW, Stagno S, Tiller RE, Alford CA (1976) Protracted pneumonitis in young infants associated with perinatally acquired cytomegaloviral infection. J Pediatr 89:16–22
Wilkinson RH, Blanc WA, Hagstrom JWC (1968) Pulmonary alveolar proteinosis in three infants. Pediatrics 41:510–515
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Schneider, K., Brünstler, I., Vogel, H. et al. Desquamative interstitial pneumonitis and alveolar lipoproteinosis: Diagnostic difficulties and therapy problems with an infant. Eur J Pediatr 145, 575–578 (1986). https://doi.org/10.1007/BF02429072
- Desquamative interstitial pneumonitis
- Alveolar lipoproteinosis
- Cytomegalovirus disease