Immobilization ofColeus blumei cells in a column reactor using a spray feeding system
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Coleus blumei cells were immobilized in a column reactor packed withLuffa cylindrica pieces. Medium was fed from the top of the column using a spray system and cells maintained high viability for 52 days. Cell growth was slower but rosmarinic acid production was better compared to immobilized cells in the shake flasks.
KeywordsRosmarinic Acid Column Reactor Fresh Cell Weight Immobilize Cell Culture Rosmarinic Acid Production
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