Skip to main content

Advertisement

SpringerLink
Log in

A hybrid method of attenuation correction for positron emission tomography brain studies

  • Original Article
  • Published:
European Journal of Nuclear Medicine Aims and scope Submit manuscript

Abstract

A hybrid method for attenuation correction (HAC) in positron emission tomography (PET) brain studies is proposed. The technique requires the acquisition of two short (1 min) transmission scans immediately before or after the emission study, with the patient and the head fixation system in place and after removing the patient from the scanner with the head fixation system alone. The method combines a uniform map of attenuation coefficients for the patient's head with measured attenuation coefficients for the head fixation system to generate a hybrid attenuation map. The HAC method was calibrated on 30 PET cerebral studies for comparison with the conventional measured attenuation correction method by ROI analysis. Average differences of less than 3% were found for cortical and subcortical regions. The HAC technique is particularly suitable in a PET clinical environment, allowing a reduction of the total study time, greater comfort for patients and an increase in patient throughput.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bergström M, Litton J, Eriksson L, Bohm C, Blomqvist G. Determination of object contour from projections for attenuation correction in cranial positron emission tomography.J Comput Assist Tomogr 1982; 6: 365–372.

    Article  PubMed  Google Scholar 

  2. Tomitani T. An edge detection algorithm for attenuation correction in emission CT.IEEE Trans Nucl Sci 1987; NS34: 309–312.

    Google Scholar 

  3. Michel C, Bol A, De Volder AG, Goffinet AM. Online brain attenuation correction in PET: towards a fully automated data handling in a clinical environment.Eur J Nucl Med 1989; 15: 712–718.

    Article  PubMed  CAS  Google Scholar 

  4. Siegel S, Dahlbom M. Implementation and evaluation of a calculated attenuation correction for PET.IEEE Trans Nucl Sci 1992; NS39: 1177–1121.

    Google Scholar 

  5. Huang SC, Hoffman EJ, Phelps ME, Kuhl DE. Quantitation in positron emission computed tomography. 2. Effects of inaccurate attenuation correction.J Comput Assist Tomogr 1979; 3: 804–814.

    Article  PubMed  CAS  Google Scholar 

  6. McCord ME, Bacharach SL, Bonow RO, Dilsizian V, Cuocolo A, Freedman M. Misalignment between PET transmission and emission scans: its effect on myocardial imaging.J Nucl Med 1992; 33: 1209–1214.

    PubMed  CAS  Google Scholar 

  7. Dahlbom M, Hoffman EJ. Problems in signal-to-noise ratio for attenuation correction in high resolution PET.IEEE Trans Nucl Sci 1987; NS34: 288–292.

    Article  Google Scholar 

  8. Carroll LR, Kretz P, Orcutt G. The orbiting rod source: improving performance in PET transmission correction scans. In: Esser PD, ed.Emission computed tomography: current trends. New York: Society of Nuclear Medicine; 1983: 235–247.

    Google Scholar 

  9. Thompson CJ, Dagher A, Lunney DN, Strother SC, Evans AC. A technique to reject scattered radiation in PET transmission scans. In: Nalcioglu O, Cho ZH, Budinger TF (eds) International workshop on physics and engineering of computerized multidimensional imaging and processing.Proc SPIE 1986;671:244–253.

    Google Scholar 

  10. Huesman RH, Derenzo SE, Cahoon JL, Geyer AB, Moses WW, Uber DC, Vuletich T, Budinger TF. Orbiting transmission source for positron tomography.IEEE Trans Nucl Sci 1988; NS35: 735–739.

    Article  Google Scholar 

  11. Kubler WK, Ostertag H, Hoverath H, Doll J, Ziegler S, Lorenz W. Scatter suppression by using a rotating pin source in PET transmission measurements.IEEE Trans Nucl Sci 1988; NS35: 749–775.

    Article  Google Scholar 

  12. Daube-Witherspoon, Carson RE, Green MV. Post-injection transmission attenuation measurements for PET.IEEE Trans Nucl Sci 1988; NS35: 757–761.

    Article  Google Scholar 

  13. Carson RE, Daube-Witherspoon ME, Green MV. A method for post-injection PET transmission measurements with a rotating source.J Nucl Med 1988; 29: 1558–1567.

    PubMed  CAS  Google Scholar 

  14. Ranger NT, Thompson CJ, Evans AC. The application of a masked orbiting transmission source for attenuation correction in PET.J Nucl Med 1989; 30: 1056–1068.

    PubMed  CAS  Google Scholar 

  15. Thompson CJ, Ranger NT, Evans AC. Simultaneous transmission and emission scan in positron emission tomography.IEEE Trans Nucl Sci 1989; NS36: 1011–1016.

    Article  Google Scholar 

  16. Thompson CJ, Ranger NT, Evans AC, Gjedde A. Validation of simultaneous PET emission and transmission scans.J Nucl Med 1990; 32: 154–160.

    Google Scholar 

  17. Huang SC, Carson RE, Phelps ME, Hoffman EJ, Schelbert HR, Kuhl DE. A boundary method for attenuation correction in positron computed tomography.J Nucl Med 1981; 22: 627–637.

    PubMed  CAS  Google Scholar 

  18. Xu EZ, Mullani NA, Gould LK, Anderson WL. A segmented attenuation correction for PET.J Nucl Med 1991; 32: 161–165.

    PubMed  CAS  Google Scholar 

  19. Meikle SR, Dahlbom M, Cherry SR. Attenuation correction using count-limited transmission data in positron emission tomography.J Nucl Med 1993; 34: 143–150.

    PubMed  CAS  Google Scholar 

  20. Bettinardi V, Scardaoni R, Gilardi MC, Rizzo G, Perani D, Paulesu E, Striano G, Triulzi F, Fazio F. Head holder for PET,CT, and MR studies.J Comput Assist Tomogr 1991; 15: 886–892.

    PubMed  CAS  Google Scholar 

  21. Ostertag H, Kubler WK, Doll J, Lorenz WJ. Measured attenuation correction methods.Eur J Nucl Med 1989; 15: 722–726.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. INB-CNR, Scientific Institute H San Raffaele, University of Milan, Milan, Italy

    Valentino Bettinardi, Maria Carla Gilardi, Giovanna Rizzo, Giuseppe Striano & Ferruccio Fazio

  2. Division of Nuclear Medicine, H. Castelfranco Veneto, Treviso, Italy

    Serena Cargnel

  3. University of Turku, Turku, Finland

    Mika Teräs

Authors
  1. Valentino Bettinardi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Maria Carla Gilardi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Serena Cargnel
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Giovanna Rizzo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Mika Teräs
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Giuseppe Striano
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Ferruccio Fazio
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bettinardi, V., Gilardi, M.C., Cargnel, S. et al. A hybrid method of attenuation correction for positron emission tomography brain studies. Eur J Nucl Med 21, 1279–1284 (1994). https://doi.org/10.1007/BF02426690

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02426690

Key words

Search

Navigation