Abstract
A new population of Mus musculus domesticus showing Robertsonian translocations (2n = 22) has been identified in Tunisia. Mice carried 9 pairs of Robertsonian translocations: Rb(1.11), Rb(2.16), Rb(3.12), Rb(4.6), Rb(5.14), Rb(7.18), Rb(8.9), Rb(10.17) and Rb(13.15). Five of the nine translocations are not known to occur elsewhere. In two populations only 2n = 22 mice were present, whereas in a third one a mixture of karyotypes (2n = 22, 38, 39, 40) was found. The slight electrophoretic differentiation observed for other Robertsonian populations as well as the hybrid nature of the karyotypically heterogeneous populations are confirmed. Allele frequency differences between the 2n = 22 and 2n = 40 mice in the latter population show that local electrophoretic differentiation exists and allow to compare chromosome flow and gene flow. The presence of a chromosome-1 polymorphism for additional fragments of heterochromatin present in the Robertsoman population provides a convenient marker of recombinational events in the hybrid zone.
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References
Adolph, S. & Klein J., 1981. Robertsonian variation in Mus musculus from Central Europe, Spain and Scotland. J. Hered. 72: 219–221.
Adolph, S., 1982. Chromosomenvariationen in Mus musculus domesticus, Rutty, aus Süddeutschland. Dissertation, Univ. Tübingen (G.F.R.) 86 p.
Bonhomme, F., Catalan, J., Britton-Davidian, J., Chapman, V. M., Moriwaki, K., Nevo, E. & Thaler, L., 1984. Biochemical diversity and evolution in the genus Mus. Biochemical Genetics 22: 275–303.
Britton-Davidian, J., Bonhomme, F., Croset, H., Capanna, E. & Thaler, L., 1980. Variabilité chez les populations de souris (genre Mus L.) à nombre chromosomique reduit. C.r. Acad. Sci. Paris 290: 195–198.
Capanna, E., Civitelli, M. V. & Cristaldi, M., 1973. Chromosomal polymorphism in an alpine population of Mus musculus L. Boll. Zool. 40: 379–383.
Capanna, E., Gropp, A., Winking, H., Noack, G. & Civitelli, M.-V., 1976. Robertsonian metacentrics in the mouse. Chromosoma 58: 341–353.
Capanna, E., Civitelli, M.-V. & Cristaldi, M., 1977a. Chromosomal rearrangement, reproductive isolation and speciation in mammals: the case of Mus musculus. Boll. Zool. 44: 213–246.
Capanna, E., Civitelli, M.-V., Cristaldi, M. & Noack, G., 1977b. New Robertsonian metacentrics in another 22-chromosome mouse population in central Apennines. Experientia 33: 173–175.
Capanna, E. & Riscassi, E., 1978. Robertsonian karyotype variability in natural Mus musculus populations in the Lombardy area of the Po valley. Boll. Zool. 45: 63–71.
Deckers, J. F. M., & Van der Kroon, P. H. W., 1981a. Some characteristics of the XO (Mus musculus L.). L. Vitality: growth and metabolism. Genetica 57: 3–11.
Deckers, J. F. M., Van der Kroon, P. H. W. & Douglas, L. Th., 1981b. Some characteristics of the XO mouse (Mus musculus L.). II. Reproduction: fertility and gametic segregation. Genetica 57: 3–11.
Dulic, B., Soldatovic, B. & Dunderski, Z., 1980. Distribution of karyotypes in Mus musculus Linnaeus, 1758 (Rodentia, Muridae) in some regions of Yougoslavia. Biosistematika 6: 203–210.
Gropp, A., Tettenborn, U. & Von Lehmann, E., 1970. Chromosomenvariation vom robertson'schen Typus bei der Tabakmaus, M. poschiavinus, und ihren Hybriden mit der Laboratorium-Maus. Cytogenetics 9: 9–23.
Gropp, A., Winking, H., Zech, L. & Muller, H. J., 1972. Robertsonian chromosomal variation and identification of metacentric chromosomes in feral mice. Chromosoma 39: 265–288.
Gropp, A., Winking, H. & Redi, C., 1982. Consequences of Robertsonian heterozygosity: segregational impairment of fertility versus male-limited sterility. In: Genetic control of gamete production and function. Eds: Crosignani, P. G.et al., pp. 115–134. Academic Press/Grune and Stratton.
Haouas, Z., T982. Contribution à l'étude biosystématique et écologique de la souris du genre Mus L. de la Medjerda. Diplôme d'études approfondies d'écologie animale, Faculté des Sciences de Tunis, 23 p.
Von Lehmann, E. & Radbruch, A., 1977. Robertsonian translocations in Mus musculus from Sicily. Experientia 33: 1025–1026.
Nash, H. R. Brooker, P. C. & Davis, S. J. M., 1983. The Robertsonian house-mouse populations of North-East Scotland: A study of their origin and evolution. Heredity 50: 303–310.
Nei, M., 1972. Genetic distance between populations. Am. Nat. 106: 283.
Nesbitt, M. N. & Francke, U., 1973. A system of nomenclature for band patterns of mouse chromosomes. Chromosoma 41: 145–158.
Pasteur, N. Techniques d'électrophorèse appliquées à la génétique des populations. In press.
Thaler, L., Bonhomme, F. & Britton-Davidian, J., 1981. Processes of Speciation and Semi-speciation in the Housemouse. Symp. zool. Soc. Lond. 47: 27–41.
Sonjaya, H., 1984. Etude des populations Robertsoniennes de souris: Analvses de la transmission d'un variant chromosomique; charactérisation d'un variant chromosomique, constitution d'une souche à 2n=38 chromosomes. Diplôme d'études supérieures, Université des Sciences et Techniques du Languedoc, Montpellier, 32 p.
Volobouev, V. T, 1983. Les types de polymorphisme chromosomique et leur rôle évolutif chez les mammifères (Insectivora, Rodentia et Carnivora). Thèse Doctorat d'état, Université Pierre et Marie Curie Paris VI, 205 p.
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Saïd, K., Jacquart, T., Montgelard, C. et al. Robertsonian house mouse populations in Tunisia: A karyological and biochemical study. Genetica 68, 151–156 (1986). https://doi.org/10.1007/BF02424412
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DOI: https://doi.org/10.1007/BF02424412