, Volume 30, Issue 3, pp 232–234 | Cite as

Complete sequences of DQA1 and DQB1 cDNA clones corresponding to the DQw4 specificity

  • Ann-Kristin Jonsson
  • Leif Andersson
  • Lars Rask
Gene-Antigen Register


cDNA Clone Complete Sequence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Auffray, C., Korman, A. J., Roux-Dosseto, M., Bono, R., and Strominger, J. L.: cDNA clone for the heavy chain of the human B cell alloantigen DC1: strong sequence homology to the HLA-DR heavy chain.Proc Natl Acad Sci USA 79: 6337–6341, 1982PubMedGoogle Scholar
  2. Auffray, C., Lillie, J. W., Arnot, D., Grossberger, D., Kappes, D., and Strominger, J. L.: Isotypic and allotypic variation of human class II histocompatibility antigen α-chain genes.Nature 308: 327–333, 1984CrossRefPubMedGoogle Scholar
  3. Chang, H.-C., Moriuchi, T., and Silver, J.: The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region.Nature 305: 813–815, 1983CrossRefPubMedGoogle Scholar
  4. Gyllensten, U. B. and Erlich, H. A.: Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.Proc Natl Acad Sci USA 85: 7652–7656, 1988PubMedGoogle Scholar
  5. Horn, G. T., Bugawan, T. L., Long, C. M., and Erlich, H. A.: Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.Proc Natl Acad Sci USA 85: 6012–6016, 1988PubMedGoogle Scholar
  6. Larhammar, D., Schenning, L., Gustafsson, K., Wiman, K., Claesson, L., Rask, L., and Peterson, P. A.: Complete amino acid sequence of an HLA-DR antigen-like β chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A,-B, and C antigens.Proc Natl Acad Sci USA 79: 3687–3691, 1982PubMedGoogle Scholar
  7. Rask, L., Andersson, D., Andersson, L., Gustafsson, K., Jonsson, A.-K., Larhammar, D., Servenius, G., and Peterson, P. A.: The evolution of human class II antigens as deduced from sequence analyses.In G. Kelsoe and D. H. Schulze (eds.):Evolution and Vertebrate Immunity. The Antigen-Receptor and MHC Gene Families. pp. 363–377, Texas University Press, 1987Google Scholar
  8. Schenning, L., Larhammar, D., Bill, P., Wiman, K., Jonsson, A.-K., Rask, L., and Peterson, P. A.: Both α and β chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains.EMBO J 3: 447–452, 1984PubMedGoogle Scholar
  9. Tabor, S. and Richardson, C. C.: DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.Proc Natl Acad Sci USA 84: 4767–4771, 1987PubMedGoogle Scholar
  10. Vieira, J. and Messing, J.: The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers.Gene 19: 259–268, 1982CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • Ann-Kristin Jonsson
    • 1
  • Leif Andersson
    • 2
  • Lars Rask
    • 1
  1. 1.Department of Cell ResearchUppsala University and Swedish University of Agricultural Sciences Biomedical CenterUppsalaSweden
  2. 2.Department of Animal Breeding and GeneticsSwedish University of Agricultural Sciences, Biomedical CenterUppsalaSweden

Personalised recommendations