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TDPAC studies of111mCd in calciproteins: Calmodulin and parvalbumin

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Abstract

TDPAC measurements of the 150–247 keV gamma-ray cascade in111Cd have been performed at room temperature on Calmodulin (CaM) and Parvalbumin (Pa) labelled with radioactive111mCd. The anisotropy of the coincidence counting rate shows a time-dependent behaviour, typical of two different nuclear quadrupole interactions (NQI) in CaM. The NQI parameters indicate the presence of two distinct metal-binding sites, presenting non-equivalent local electric charge structure. In Pa samples, only one NQI is observed and the measured electric field gradient (EFG) value agrees well with the large one obtained in CaM.

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Authors and Affiliations

  1. Faculté de Médecine Necker-Enfants Malades, Laboratoire de Biophysique, 156 rue de Vaugirard, 75730, Paris Cédex 15, France

    J. N. Rimbert, F. Adnet, C. Lafargue & F. Dumas

  2. Laboratoire de Biochimie, C.H.U. Saint-Antoine, 27, rue Chaligny, 75771, Paris Cédex 12, France

    C. Wolf & G. Bereziat

Authors
  1. J. N. Rimbert
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  2. F. Adnet
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  3. C. Lafargue
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  4. F. Dumas
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  5. C. Wolf
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  6. G. Bereziat
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Rimbert, J.N., Adnet, F., Lafargue, C. et al. TDPAC studies of111mCd in calciproteins: Calmodulin and parvalbumin. Hyperfine Interact 61, 1227–1230 (1990). https://doi.org/10.1007/BF02407608

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  • DOI: https://doi.org/10.1007/BF02407608

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