Abstract
Ornithine decarboxylase (ODC), the first enzyme in the polyamine biosynthetic pathway, is encoded by at least one member of a multi-gene family in the mouse. Analysis of a polymorphism in ODC structure in recombinant inbred strains has enabled assigning a functional ODC structural gene (Odc) to the proximal region of mouse chromosome 12 betweenApob andEs25. Linkage ofOdc toApob andAh is conserved in the mouse and human genomes.
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This work was supported by Grant DK37265 from the National Institutes of Health.
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Berger, F.G. Assignment of a gene encoding ornithine decarboxylase to the proximal region of chromosome 12 in the mouse. Biochem Genet 27, 745–753 (1989). https://doi.org/10.1007/BF02396065
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DOI: https://doi.org/10.1007/BF02396065