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Zur Morphologie der Nierentumoren bei der Ratte

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Zusammenfassung

Verschiedene Nitrosamine und Nitrosamide erzeugen Nierentumoren bei der Ratte (Tabelle 1), wenn sie in hohen Einzeldosen einmalig oder nur für kurze Zeit zugeführt werden. Histologisch handelt es sich um epitheliale Geschwülste und um Mischtumoren vom Typ der Nephroblastome. Die Tumoren werden mit den in der Literatur beschriebenen spontanen und experimentell erzeugten Nierengeschwülsten verglichen.

Summary

Various nitrosamines and nitrosamides cause renal tumors in the rat (Table 1), if these agents are administered in high single doses once, or only for a short time. Histologically the tumors are both epithelial and mixed tumors of the nephroblastoma type. The tumors are compared with those renal tumors reported in the literature occurring either spontaneously or induced experimentally.

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Authors and Affiliations

  1. Pathologischen Institut der Universität Bonn, Bonn, Deutschland

    C. Thomas & D. Schmähl

  2. dem Laboratorium der Chirurgischen Klinik der Universität Freiburg, Freiburg, Deutschland

    C. Thomas & D. Schmähl

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  1. C. Thomas
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  2. D. Schmähl
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Thomas, C., Schmähl, D. Zur Morphologie der Nierentumoren bei der Ratte. Z Krebs-forsch 66, 125–137 (1964). https://doi.org/10.1007/BF02395338

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  • DOI: https://doi.org/10.1007/BF02395338

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