Long acting nifedipine in the treatment of severe hypertension
The medication of patients receiving hydralazine, captopril and minoxidil was replaced by a new galenical form, long-acting nifedipine. An additional decrease in blood pressure was observed in most of the patients. Renal function was maintained in all of them. Adverse reactions may be reduced by the use of long-acting nifedipine, which would permit a reduction in the dosage of captopril and minoxidil.
Key wordsnifedipine hypertension blood pressure decrease drug combination
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- 5.Corvol P, Marre M, Banzet O, Colin JN, Thibonnier M, Singlas E, Alexandre JM (1983) Acute antihypertensive effects and pharmacokinetic parameters of a new galenic form of nifedipine in the 5th International Adalat Symposium. Kaltenbach M, Neufeld HN (eds). Excerpta MedicaGoogle Scholar
- 7.Buhler FR, Sealey JE, Laragh JH (1974) Radioimmunoassay of plasma aldosterone. In: Laragh JH (ed) Hypertension manual York Medical Books, New York, p 655Google Scholar
- 8.Brunner HR, Sealey JE, Laragh JH (1974) Renin as a risk factor in essential hypertension: more evidence. In: Laragh JH (ed) Hypertension manual York Medical Books, New York, pp 71–75Google Scholar
- 9.Ueda K, Murakami M (1983) A controlled, comparative multicenter study on the clinical efficacy of nifedipine in the treatment of severe hypertension in the 5th International Adalat Symposium Kaltenbach M, Neufeld HN (eds). Excerpta Medica pp 146–155Google Scholar
- 11.Olivari MT, Bartorelli C, Polese A, Fiorentini C, Moruzzi P, Guazzi D (1979) Treatment of hypertension with nifedipine, a calcium antagonist agent circulation 59: 1056–1062Google Scholar
- 12.Hedland A, Heidbreder E, Horl WH, Schafer R (1982) Calcium antagonists in the treatment of hypertension Contrib Nephrol 33: 254–269Google Scholar
- 14.Lynch P, Dargie H, Krikler S, Krikler D (1980) Objective assessment of antianginal treatment: a double-blind comparison of propranolol, nifedipine, and their combination. Br Med J 280: 184–187Google Scholar
- 15.Millar JA, Reid JL (1983) Decreased vascular and adrenal responses to angiotensin II after administration of nifedipine in the 5th International Adalat Symposium. Kaltenbach M, Neufeld HN (eds). Excerpta Medica, pp 122–129Google Scholar