Neuroscience and Behavioral Physiology

, Volume 26, Issue 1, pp 98–101 | Cite as

Influence of repeated exposures to stress on the sensitivity of the organism to glucocorticoids and insulin

  • V. É. Tseilikman
  • I. A. Volchegorskii
  • O. L. Kolesnikov
  • I. A. Vyazovskii
  • I. A. Gienko
  • A. A. Kolesnikova
  • O. A. Afans'ev
  • R. I. Lifshits
Article
  • 12 Downloads

Conclusions

  1. 1.

    A simultaneous decrease in the sensitivity of the organism to exogenous glucocorticoids and an increase in insulin sensitivity takes place during repeated exposures to stress.

     
  2. 2.

    The pharmacological blockade of the adrenoreceptors during repeated exposures to stress increases insulin resistance.

     

Keywords

Insulin Resistance Glucocorticoid Insulin Sensitivity Repeated Exposure Simultaneous Decrease 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    O. M. Avakyan,The Pharmacological Regulation of the Function of the Adrenoreceptors [in Russian], Moscow (1988).Google Scholar
  2. 2.
    I. A. Volchegorskii, Yu. K. Kostin, N. A. Skobeleva, and R. I. Lifshits,Probl. Éndokrinol., No. 4, 75–79 (1993).Google Scholar
  3. 3.
    J. H. Glynn,Cortisone Therapy [Russian translation], Moscow (1960).Google Scholar
  4. 4.
    P. P. Golikov,The Receptor Mechanism, of the Glucorticoid Effect [in Russian], Moscow (1988).Google Scholar
  5. 5.
    E. V. Gubler, and A. A. Genkin,The Use of Nonparametric Statistical Tests in Medical Research [in Russian], Leningrad (1973).Google Scholar
  6. 6.
    Yu. K. Kostin, V. S. Grigorevskikh, I. A. Volchegorskii, and R. I. Lifshits,Pat. 1,793,918, 1993. A Method of Insulin Coma Therapy [in Russian].Google Scholar
  7. 7.
    D. N. Mayanskii,Chronic Inflammation [in Russian], Moscow (1991).Google Scholar
  8. 8.
    F. Z. Meerson and M. G. Pshennikova,Adaptation to Physical Loads and Stress Situations [in Russian] Moscow (1987).Google Scholar
  9. 9.
    L. E. Panin,Biochemical Mechanisms of Stress [in Russian], Novosibrisk (1983).Google Scholar
  10. 10.
    B. I. Sasu, N. A. Mukhin, V. N. Lyashko, and M. I. Freidlin,Byul. Éksper. Biol., No. 1, 75–79 (1984).Google Scholar
  11. 11.
    P. V. Sergeev and N. L. Shimanovskii,The Receptors [in Russian], Moscow (1987).Google Scholar
  12. 12.
    J. Tepperman and H. Tepperman,Metabolic and Endocrine Physiology [Russian translation], Moscow (1989).Google Scholar
  13. 13.
    L. N. Shishkina, D. N. Mayanskii, G. V. Shutko, and P. V. Sergeev, Byul. Éksper. Biol. No. 1, 76–78 (1985).Google Scholar
  14. 14.
    Fang Cheng-Hui, Sun Yong-Hua, Zhu Zhao-nung, and Cheng Zhi-yong,Chin. Med.,104, No. 9, 782–788 (1991).Google Scholar

Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • V. É. Tseilikman
  • I. A. Volchegorskii
  • O. L. Kolesnikov
  • I. A. Vyazovskii
  • I. A. Gienko
  • A. A. Kolesnikova
  • O. A. Afans'ev
  • R. I. Lifshits

There are no affiliations available

Personalised recommendations