Cholangiocellular carcinoma in a patient who has survived for 6 years after extended left hepatic lobectomy and caudate lobe resection with pancreatoduodenectomy
- 40 Downloads
We describe a case of cholangiocellular carcinoma in a 66-year-old woman. A well-defined, hypoechoic tumor, 9 cm in greatest diameter, was detected in the left lobe of the liver by ultrasonography in December 1988. Celiac angiography showed a faintly stained tumor at the same location, with interruption of the left portal vein. Computed tomography revealed invasion of the inferior vena cava and lymph node enlargement around the head of the pancreas. In January 1989, the patient underwent extended left hepatic lobectomy with caudate lobe resection, pancreatoduodenectomy, partial resection of the inferior vena cava, and lymph node dissection around the hepatoduodenal ligament and the common hepatic artery. Postoperative histopathological examination revealed a moderately differentiated tubular adenocarcinoma. Cancer cells had invaded only the portal region, unlike the features of most cholangiocellular carcinomas. There was no evidence of lymph node metastasis in the dissected specimens. Six years after operation, there have been no signs of recurrence, and the patient is still alive and well.
Key wordscholangiocellular carcinoma long-term survival portal area invasion
Unable to display preview. Download preview PDF.
- 5.Craig JR, Peters RL, Edmondson HA (1989) Cholangiocarcinoma. In: Craig JR, Peters RL, Edmondson HA (eds) Tumors of the liver and intrahepatic bile ducts. Atlas of tumor pathology, fascicle 26. Armed Forces Institute of Pathology, Washington, D.C., pp 197–211Google Scholar
- 7.Taguchi J (1994) Clinicopathologic study of 26 resected cases of cholangiocarcinoma (in Japanese with English abstract). Kanzou (Acta Hepatol Jpn) 35:737–744Google Scholar
- 8.Nagaoka T, Ohkawa S, Ito Y, Tamai S, Tarao K, Sugimasa Y, Takemiya S, Okamoto T, Kameda Y, Yamaguchi M, Iida M (1991) A case of minute cholangiocellular carcinoma found in follow-up of liver cirrhosis and which was indistinguishable from hepatocellular carcinoma on hepatic angiography (in Japanese). Nippon Shoukakibyo Gakkai Zasshi (Jpn J Gastroenterol) 88: 1369–1374Google Scholar
- 10.Takasaki K, Kobayashi S, Mutoh H, Akimoto S, Toda S, Asado Y, Fukushima E, Yoshikawa T, Imaizumi T, Sato Y, Takada T, Nakamura M, Hanyu F (1980) Our experience (five cases) of extended right lobectomy combined with pancreato-duodenectomy for carcinoma of gallbladder (in Japanese). Tan to Sui (Biliary Tract and Pancreas) 1:923–932Google Scholar
- 11.Sugiura Y, Shima S, Yonekawa H, Ogata T (1982) Post-surgical management of hepatopancreatoduodenectomy (in Japanese). Nippon Shokaki Gekagakkai Zasshi (Jpn J Gastroenterol Surg) 15:1631–1635Google Scholar