Archives of Gynecology and Obstetrics

, Volume 255, Issue 3, pp 141–146 | Cite as

Primary Fallopian tube carcinoma — a retrospective survey of 51 cases

  • M. Klein
  • A. Rosen
  • A. Graf
  • M. Lahousen
  • H. Kucera
  • B. Pakisch
  • N. Vavra
  • A. Beck
Originals

Abstract

Objective: To evaluate retrospectively the importance of invasion beyond the basement membrane on overall survival in Fallopian tube carcinoma and its influence on the necessity of postoperative adjuvant therapy (stage 0 vs. stage I).Design: In a nationwide analysis the data of 51 patients were evaluated. The participating departments provided the study center with histologic specimens. A re-staging was done according to the FIGO-classification for Fallopian tube carcinomas. Stage 0 patients received no further postoperative therapy, in stage I patients were devided in 2 groups to evaluate the impact of postoperative adjuvant therapy (chemotherapy vs. irradiation).Results: Patients of stage 0 had a significantly better prognosis than patients of stage I (p=0.035). Stage I patients treated by irradiation showed a significantly better prognosis than patients treated by chemotherapy (p=0.017).Conclusion: Tumour penetration through the basement membrane causes prognosis to deteriorate significantly (5-year survival rate about 50% in stage I). Postoperative therapy is thus indicated with stage I disease. Irradiation seems to give better results than chemotherapy.

Key words

Fallopian tube carcinoma Stage 0 Stage I Chemotherapy Irradiation 

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • M. Klein
    • 6
  • A. Rosen
    • 1
  • A. Graf
    • 2
  • M. Lahousen
    • 3
  • H. Kucera
    • 4
  • B. Pakisch
    • 5
  • N. Vavra
    • 4
  • A. Beck
    • 6
  1. 1.Department of GynecologyDonauspitalViennaAustria
  2. 2.Department of GynecologyLKH SalzburgAustria
  3. 3.Department of GynecologyUniversity of GrazAustria
  4. 4.1st Department of GynecologyUniversity of ViennaAustria
  5. 5.Department of RadiotherapyLKH Wr. NeustadtAustria
  6. 6.Department of GynecologyHanusch-KrankenhausViennaAustria

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