Pediatric Radiology

, Volume 18, Issue 3, pp 190–193 | Cite as

Intrathecal administration of iopamidol in children: clinical and diagnostic results

  • R. G. Wells
  • F. G. Seidel
  • J. R. Sty
  • H. M. Swick


An open label, noncomparative clinical trial of intrathecal iopamidol in children was performed. Sixty-one subjects between the ages of 24 days and 17 years were studied. Opacification of the subarachnoid space was adequate in all cases. Mild adverse reactions were detected in 10% of the participants. Seizures, EEG alterations or other severe reactions did not occur. The findings confirm the efficacy and safety of iopamidol as an intrathecal contrast medium in pediatrics.


Public Health Clinical Trial Contrast Medium Adverse Reaction Subarachnoid Space 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Pettersson H, Fitz CR, Harwood-Nash CF, Armstrong E, Chuang SH (1982) Adverse reactions to myelography with metrizamide in infants, children and adolescents. Acta Radiol [Diagn] 23: 323Google Scholar
  2. 2.
    Swick HM, Sty JR, Haughton VM (1978) Clinical evaluation of metrizamide for neuroradiology in children. Ann Neurol 3: 409CrossRefPubMedGoogle Scholar
  3. 3.
    Lamb JT, Holland IM (1983) Myelography with iopamidol. AJNR 4: 851PubMedGoogle Scholar
  4. 4.
    Drayer B, Suslavich F, Luther J et al (1982) Clinical trial of iopamidol for lumbosacral myelography. AJNR 3: 59PubMedGoogle Scholar
  5. 5.
    Drayer BP, Warner MA, Sudilovsky A et al (1982) lopamidol vs metrizamide: a double blind study for cervical myelography. Neuroradiology 24: 77CrossRefPubMedGoogle Scholar
  6. 6.
    Turski PA, Sackett JF, Gentry LR, Strother CM, Matozzi F (1983) Clinical comparison of metrizamide and iopamidol for myelography. AJNR 4: 309PubMedGoogle Scholar
  7. 7.
    Keiffer SA, Binet EF, Davis DO et al (1984) Lumbar myelography with iohexol and metrizamide: a comparative multicenter prospective study. Radiology 151: 665Google Scholar
  8. 8.
    Tourtellotte WW, Haerer AE, Heller GL, Somers JE (1964) Post-lumbar puncture headaches. Charles C Thomas, SpringfieldGoogle Scholar
  9. 9.
    Kendall B (1986) Iohexol in paediatric myelography. An open non-comparative trial. Neuroradiology 28: 65PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • R. G. Wells
    • 3
  • F. G. Seidel
    • 2
  • J. R. Sty
    • 3
  • H. M. Swick
    • 1
  1. 1.Department of NeurologyChildren's Hospital of WisconsinMilwaukeeUSA
  2. 2.Department of RadiologyChildren's Hospital of BuffaloBuffaloUSA
  3. 3.Department of RadiologyChildren's Hospital of WisconsinMilwaukeeUSA

Personalised recommendations