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Permeation of Cs+ ions across skin barriers

  • Fractionation of Radionuclides and Metals in Environmental Systems (Transfer and Speciation)
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Abstract

Permeation of metal Cs+ ions from water solutions across the intact, stripped and splitted skin of 5- or 9-day old rat was studiedin vitro using vertical diffusion cells. The results showed that the stratum corneum (horny layer) of this new animal skin model represents the principal pentration barrier. The relative importance of the percutaneous absorption of Cs+ ions through transepidermal and transfolicular routes has been assessed comparing the penetration across skin without hairs and skin just haired. The results have shown that the shunt diffusion along hair follicles can be of preponderant value.

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Authors and Affiliations

  1. Faculty of Chemical Technology, Slovak Technical University, Bratislava, Slovak Republic

    V. Koprda & M. Harangozó

  2. Institute of Experimental Pharmacology, Slovak Academy of Sciences, Bratislava, Slovak Republic

    L'. Boháčik

Authors
  1. V. Koprda
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  2. M. Harangozó
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  3. L'. Boháčik
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Koprda, V., Harangozó, M. & Boháčik, L. Permeation of Cs+ ions across skin barriers. J Radioanal Nucl Chem 229, 91–93 (1998). https://doi.org/10.1007/BF02389453

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  • DOI: https://doi.org/10.1007/BF02389453

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