Pediatric Radiology

, Volume 19, Issue 3, pp 151–156 | Cite as

The CT and MR evaluation of migrational disorders of the brain

Part I. Lissencephaly and pachygyria
  • Sharon E. Byrd
  • R. E. Osborn
  • T. P. Bohan
  • T. P. Naidich


The migrational disorders are a rare group of congenital malformations of the brain. They consist of the following entities — lissencephaly (agyriapachygyria), pachygyria, schizencephaly, heterotopia and polymicrogyria. We studied 40 children with migrational disorders radiologically with CT and MR. This article (part I) deals with our patients with lissencephaly and pachygyria. It emphasizes their characteristic CT and MR findings along with their clinical presentation and course. These patients presented with one or a combination of the following symptoms, hypotonia, seizures, failure to thrive, microcephaly and occasionally hydrocephalus. These two groups of migrational disorders have abnormalities affecting the gyral-sulcal pattern of the cortex and gray-white matter distribution of the brain. MR provided better delineation of these disorders than CT. Because some forms of the migrational disorders can be inherited, it is extremely important for the radiologist to understand the characteristic findings for correct diagnosis which is essential for parental counseling.


Public Health Hydrocephalus Correct Diagnosis Congenital Malformation Microcephaly 
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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • Sharon E. Byrd
    • 4
  • R. E. Osborn
    • 1
  • T. P. Bohan
    • 2
  • T. P. Naidich
    • 3
  1. 1.Department of RadiologyNaval HospitalSan Diego
  2. 2.Departments of Pharmacology and NeurologyThe University of Texas Health Science CenterHouston
  3. 3.Department of RadiologyBaptist Hospital of MiamiMiamiUSA
  4. 4.Division of Neuroimaging Department of RadiologyChildren's Memorial Hospital Northwestern University Medical SchoolChicagoUSA

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