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Hepatic imaging in Stage IV-S neuroblastoma

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Abstract

Stage IV-S neuroblastoma describes a group of infants with tumor spread limited to liver, skin, or bone marrow. Such patients, who constitute about 25% of affected infants with neuroblastoma, may expect spontaneous tumor remission. We report 18 infants with Stage IV-S neuroblastoma, 83% of whom had liver involvement. Imaging investigations included Technetium 99m sulfur colloid scan, ultrasound, and CT. Two patterns of liver metastasis were noted: ill-defined nodules or diffuse tumor throughout the liver. Distinction of normal and abnormal liver with diffuse type metastasis could be quite difficult, particularly with liver scans. We conclude that patients with Stage IV-S neuroblastoma have ultrasound or CT examination as an initial workup, with nuclear medicine scans reserved for followup studies.

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Authors and Affiliations

  1. Department of Radiology, University of Iowa College of Medicine, Iowa City, Iowa

    E. A. Franken Jr. & W. L. Smith

  2. Department of Pediatrics, University of Iowa College of Medicine, Iowa City, Iowa

    W. L. Smith & C. T. Kisker

  3. Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa

    C. E. Platz

  4. Department of Pediatric Radiology, James Whitcomb Riley Hospital, Indianapolis, Indiana, USA

    M. D. Cohen

  5. Department of Radiology, University of Iowa Hospitals, 52242, Iowa City, Iowa, USA

    E. A. Franken Jr.

Authors
  1. E. A. Franken Jr.
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  2. W. L. Smith
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  3. M. D. Cohen
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  4. C. T. Kisker
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  5. C. E. Platz
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Franken, E.A., Smith, W.L., Cohen, M.D. et al. Hepatic imaging in Stage IV-S neuroblastoma. Pediatr Radiol 16, 107–109 (1986). https://doi.org/10.1007/BF02386630

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  • DOI: https://doi.org/10.1007/BF02386630

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