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Comparison of whole blood, plasma and nails as monitors for the dietary intake of selenium

  • Applications of Radioanalytical Methods to Biological and Clinical Systems
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Abstract

The measurement of dietary selenium intake in a free-living population using dietary recall techniques has been shown to be spurious. Consequently, in our laboratory, we have focused on the development of biologic monitors such as blood, nails, hair and urine. In this paper, we report on the neutron activation analysis of whole blood, plasma and nail specimens collected from 285 Caucasian subjects, all permanent residents of Hawaii, participating in a malignant melanoma trial. Correlations between monitors are presented and discussed in the context of selenium determinants and integration of selenium intake.

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Authors and Affiliations

  1. University of Missouri Research Reactor Center, Research Park, 65211, Columbia, MO, USA

    M. M. Mason, J. S. Morris, V. L. Spate, C. K. Baskett, T. A. Nichols & T. L. Horsman

  2. Cancer Research Center of Hawaii, University of Hawaii at Manoa, Room 407, 1236 Lauhala St., 96813, Honolulu, HI, USA

    L. Le Marchand, L. N. Kolonel & S. Yukimoto

Authors
  1. M. M. Mason
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  2. J. S. Morris
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  3. V. L. Spate
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  4. C. K. Baskett
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  5. T. A. Nichols
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  6. T. L. Horsman
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  7. L. Le Marchand
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  8. L. N. Kolonel
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  9. S. Yukimoto
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Mason, M.M., Morris, J.S., Spate, V.L. et al. Comparison of whole blood, plasma and nails as monitors for the dietary intake of selenium. J Radioanal Nucl Chem 236, 29–34 (1998). https://doi.org/10.1007/BF02386313

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  • DOI: https://doi.org/10.1007/BF02386313

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