Abstract
The deformity or fracture of the spines, bone mineral density (BMD) of radius and spines by anterior-posterior scans and lateral scans, and metabolic bone markers were examined in the old women. The probability of fracture was less than 10% in women with L3 BMD over 0.786g/cm2, and new fractures were not found during 12 months follow-up in these patients. Among the various metabolic parameters, bone Gla protein (BGP)/hydroxyproline (Hp) excretion ratio was one of the clinically useful indices if combined with BMD. The intensive therapy may not be necessary to patients with low BMD if they show high BGP/Hp ratio. Patients with low BMD and low BGP/Hp ratio should be treated intensively in the old women.
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References
Siu H.L., Charles S.W., Conrad J.C. Jr. Age and bone mass as predictors of fracture in a prospective study. J Clin Invest 81: 1804–1809, 1990
Sandor T., Felsenberg D., Kalender W.A. et al.: Compact and trabecular components of the spine using quantitative computed tomography. Calcif Tissue Int 50: 502–506, 1992
Riggs B.L., Wahner H.W., Offord K.P. et al.: Changes in bone mineral density of the proximal femur and spine with aging. J Clin Invest 70: 716–723, 1982
Nordin B.E.C: The definition and diagnosis of osteoporosis. Calcif Tissue Int 40: 57–58, 1987
Yuh I., Yamamoto I., Ohnaka Y., et al.: Determination of vertebral fracture threshold by measuring bone mineral content in the lumbar vertebrae. Nippon Act. Radiol. 52: 217–222, 1992
Slosman D.O., Rizzoli R., Donath A., et. al.: Vertebral bone mineral density measured laterally by dual energy X-ray absorptiometry. Osteoporosis Int. 1: 23–29, 1990
Reid I.R., Evans M.C., Ames R., et al.: The influence of osteophytes and aortic calcification on spinal mineral density in postmenopausal women. J Clin Endocrinol Metab 72: 1372–1374, 1991
Nakamura T, Orimo H.: Physical and pathological aging in bone: contribution of risk factors to bone loss with aging. Jpn J Geriat 28: 318–324, 1991
Nakatsuka K, Miki T, Nishizawa Y et al. Characteristics of biochemical markers for bone formation in the elderly. J Bone Miner Metab 19: 145–151, 1992
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Miki, T., Iba, K., Futami, E. et al. The spinal bone fracture of the aged women. J Bone Miner Metab 11, S31–S35 (1993). https://doi.org/10.1007/BF02383841
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DOI: https://doi.org/10.1007/BF02383841