, Volume 19, Issue 2, pp 371–378 | Cite as

Antithrombin III activity in baboons

  • Milka M. Montiel
  • David L. McGlasson
Short Communications


The antithrombin III-heparin cofactor activity of 65 baboons and 130 healthy human subjects was measured. The results indicate that antithrombin III-heparin cofactor activity is significantly lower in baboons than in humans.

The increased activity of the coagulation system of baboon is coupled with decreased antithrombin III-heparin cofactor activity. In humans each of these changes is associated with increased risk of thrombosis, but the baboon has a very low risk of developing thrombosis. Other factors probably balance the coagulation-coagulation inhibition systems in baboons.


Human Subject Animal Ecology Antithrombin Inhibition System Coagulation System 
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Copyright information

© Japan Monkey Centre 1978

Authors and Affiliations

  • Milka M. Montiel
    • 1
  • David L. McGlasson
    • 1
  1. 1.Department of PathologyThe University of Texas Health Science CenterSan AntonioU.S.A.

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