Power and limits of DNA-profiling in primate populations: Paternity assessment in rhesus macaques from Cayo Santiago
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Paternity testing was performed in one social group (S) of rhesus macaques from Cayo Santiago, Puerto Rico. In 11/15 cases, sires could be identified comparing the multilocus DNA profiles of 19 males to those of the corresponding mother/child dyads. All 19 males could be excluded from paternity in the remaining four cases. Decision making was partly based on likelihoods of DNA profiles, and the theoretical model underlying these calculation is described. In a second social group (M), held in captivity, paternity testing was impeded by a deficit of maternal bands and by an increased extent of band sharing of mothers and their infants. Some possible explanations for these findings, including increased homozygosity in group M, are discussed.
Key WordsDNA fingerprinting Oligonucleotides Paternity assessment Heterozygosity Rhesus monkeys
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- Bockel, B., P. Nürnberg, &M. Krawczak, 1992. Likelihoods of multilocus DNA fingerprints in extended families.Amer. J. Human Genet., 51: 554–561.Google Scholar
- Cohen, J. E., 1990. DNA fingerprinting for forensic identification: potential effects on data interpretation of subpopulation heterogeneity and band number variability.Amer. J. Human Genet., 46: 358–368.Google Scholar
- Epplen, J. T., 1992. The methodology of multilocus DNA fingerprinting using radioactive or non-radioactive oligonucleotide probes specific for simple repeat motifs. In:Advances in Electrophoresis,A. Chrambach,M. J. Dunn, &B. J. Radola (eds.), VCH, Weinheim, pp. 59–114.Google Scholar
- ————,H. Ammer, C. Epplen, C. Kammerbauer, R. Mitreiter, L. Roewer, W. Schwaiger, V. Steimle, H. Zischler, E. Albert, A. Andreas, B. Beyermann, W. Meyer, J. Buitkamp, I. Nanda, M. Schmid, P. Nürnberg, S. D. J. Pena, H. Pöche, W. Sprecher, M. Schartl, K. Weising, &A. Yassourdis, 1991. Oligonucleotide fingerprinting using simple repeat motifs: a convenient, ubiquitously applicable method to detect hypervariability for multiple purposes. In:DNA Fingerprinting: Approaches and Applications,T. Burke,G. Dolf,A. J. Jeffreys, &R. Wolff (eds.), Birkhäuser, Basel, pp. 50–69.Google Scholar
- ————,M. Turner, &P. Debenham, 1991. The efficiency of multilocus DNA fingerprint probes for individualization and establishment of family relationships, determined from extensive casework.Amer. J. Human Genet., 48: 824–840.Google Scholar
- ————,I. Böhm, P. Nürnberg, J. Hampe, J. Hundrieser, H. Pöche, C. Peters, R. Slomski, J. Kwiatkowska, M. Nagy, A. Pöpperl, J. T. Epplen, &J. Schmidtke, 1992. Paternity testing with oligonucleotide multilocus probe (CAC)5/(GTG)5: a multi-center study.Forensic Sci. Int., 59: 101–117.Google Scholar
- Martin, R. D., A. F. Dixon, &E. J. Wickings (eds.), 1992.Paternity in Primates: Genetic Tests and Theories - Implications of Human DNA Fingerprinting. Karger AG, Basel.Google Scholar
- Rawlins, R. G. &M. J. Kessler (eds.), 1986.The Cayo Santiago Macaques: History, Behavior, and Biology. State Univ. of New York Press, Albany.Google Scholar