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Hb bali (Macaca) β80 (EF 4) Asn→Lys: The first hemoglobin variant found in the crab-eating monkey (Macaca fascicularis) on Bali Island, Indonesia

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Abstract

A variant hemoglobin due to structural change in the β chain was found in the central part of Bali island, Indonesia, during field studies on the genetic variation of the Indonesian crabeating monkey (Macaca fascicularis), and was named Hb Bali (Macaca). Structural analysis yielded the following results. (1) The amino acid sequence of the normal β chain of the crab-eating monkey coincided with that of the Japanese monkey (M. fuscata) and the pig-tailed monkey (M. nemestrina). (2) Asn at the 80th position from the amino terminal of the β chain was substituted by Lys in Hb Bali. This substitution appeared to have little harmful effect on the carrier, since the hematological characteristics of the heterozygous carriers were not different from those of normal individuals.

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Author notes

  1. Osamu Takenaka, Akiko Takenaka & Ken Nozawa

    Present address: Primate Research Institute, Kyoto University, Inuyama, 484, Aichi, Japan

  2. Kenji Takahashi

    Present address: Department of Biophysics and Biochemistry, Faculty of Science, The University of Tokyo, Hongo, Bunkyo-ku, 113, Tokyo, Japan

  3. Yoshi Kawamoto

    Present address: Laboratory of Animal Genetics, Faculty of Agriculture, Nagoya University, Chikusa-ku, Nagoya, 464, Aichi, Japan

Authors and Affiliations

  1. Primate Research Institute, Kyoto University, Inuyama, 484, Aichi, Japan

    Kenji Takahashi & Yoshi Kawamoto

Authors
  1. Osamu Takenaka
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  2. Akiko Takenaka
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  3. Kenji Takahashi
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  4. Yoshi Kawamoto
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  5. Ken Nozawa
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Takenaka, O., Takenaka, A., Takahashi, K. et al. Hb bali (Macaca) β80 (EF 4) Asn→Lys: The first hemoglobin variant found in the crab-eating monkey (Macaca fascicularis) on Bali Island, Indonesia. Primates 26, 464–470 (1985). https://doi.org/10.1007/BF02382460

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  • DOI: https://doi.org/10.1007/BF02382460

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