Abstract
A homologous double-antibody radioimmunoassay developed for humans was used to measure serum prolactin, progesterone, and estradiol in common marmosets. In the ovarian cycle of common marmosets, serum progesterone began to increase after an estradiol surge, attained a peak level, and then declined before the ensuing pre-ovulatory rise in estradiol. During the luteal phase, the change in serum concentrations of estradiol was synchronized with that of progesterone. During the ovarian cycle there was no consistent change in serum prolactin concentrations. During the last 75 days of pregnancy the prolactin level was higher than during the ovarian cycle and the first 70 days of pregnancy. Moreover, during lactation, mothers with suckling twin infants had a higher prolactin level than during the final stage of pregnancy.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Aono, T., T. Shioji, T. Shoda, &K. Kurachi, 1977. The initiation of human lactation and prolactin response to suckling.J. Clin. Endocrinol. Metab., 44: 1101–1106.
Aso, T., T. Motohashi, M. Matsuoka, J. H. Su, K. Murata, H. Ohsako, &Y. Imura, 1978. Influence of sulpiride on pituitary-ovarian function in human.Acta Obst. Gynaec. Jpn, 30: 281–282.
————,J. H. Su, K. Horie, S. Taira, T. Motohashi, &T. Nishimura, 1982. Influence of sulpiride-induced hyperprolactinemia on baboon menstrual cycles: a longitudinal study.J. Med. Primatol., 11: 20–34.
————, ————,M. Matsuoka, T. Motohashi, &T. Nishimura, 1979. The baboon as an animal model for research of human reproduction: The changes of plasma prolactin levels under various condition.Acta Obstet. Gynaec. Jpn, 31: 552–558.
Butler, W. R., L. C. Krey, K.-H. Lu, W. D. Peckham, &E. Knobil, 1975. Surgical disconnection of the medial basal hypothalamus and pituitary function in the rhesus monkey: IV. Prolactin secretion.Endocrinology, 96: 1099–1105.
Franchimont, P., C. Dourcy, J. J. Legros, A. Reuter, Y. Vrindts-Gevaert, J. R. van Cauwenberge, &U. Gaspard, 1976. Prolactin levels during the menstrual cycle.Clin. Endocrinol., 5: 643–650.
Harding, R. D., M. J. Holme, S. F. Lunn, C. Henderson, &R. J. Aiitken, 1982. Plasma progester-one levels throughout the ovarian cycle of the common marmoset (Callithrix jacchus).J. Med. Primatol., 11: 43–51.
Harlow, C. R., S. Gems, J. K. Hodges, &J. P. Hearn, 1983. The relationship between plasma progesterone and the timing of ovulation and early embryonic development in the marmoset monkey (Callithrix jacchus).J. Zool. London, 301: 273–282.
Hearn, J. P., 1983. The common marmoset (Callithrix jacchus). In:Reproduction in New World Primates,J. P. Hearn (ed.), MTP Press, Lancaster, pp. 183–215.
———— &S. F. Lunn, 1975. The reproductive biology of the marmoset monkey,Callithrix jacchus.Lab. Anim. Handbook, 6: 191–202.
Kholkute, S. D., 1984. Plasma progesterone levels throughout the ovarian cycle of the common marmoset (Callithrix jacchus).Primates, 25: 123–126.
————,R. P. Patil, M. P. Desai, &C. P. Puri, 1988. Metachlopromide-induced hyperprolactinemia fails to affect ovarian cycle in the common marmosets (Callithrix jacchus).Primates, 29: 549–555.
McNeilly, A. S., D. H. Abbott, S. F. Lunn, P. C. Chambers, &J. P. Hearn, 1981. Plasma prolactin concentrations during the ovarian cycle and lactation and their relationship to return of fertility post partum in the common marmoset (Callithrix jacchus).J. Reprod. Fertil., 62: 353–360.
Onda, H., 1984. A clinical study on the characteristics of galactorrhea-amenorrhea (especially of drug-induced galactorrhea-amenorrhea).Acta Obst. Gynaec. Jpn, 36: 1851–1860.
————,H. Sako, Y. Okamoto, K. Hamada, &T. Sugawa, 1983. Therapeutic effect of sulpiride (dogmatyl®) on endometriosis.Adv. Obstet. Gynecol., 35: 237–244.
Siddall, R. A., 1978. The use of marmoset (Callithrix jacchus) in teratological and toxicological research.Prim. Med., 10: 215–224.
Torii, R., H. Koizumi, &Y. Tanioka, 1987. Serum LH, progesterone and estradiol-17β levels throughout the ovarian cycle, during the early stage of pregnancy and after the parturition and the abortion in the common marmoset,Callithrix jacchus.Primates, 28: 229–238.
————,H. Nigi, H. Koizumi, &Y. Tanioka, 1989. Serum chorionic gonadotropin, progesterone and estradiol-17β levels during pregnancy in the common marmoset,Callithrix jacchus.Primates, 30: 207–215.
Tyson, J. E., P. Hwang, H. Guyda, &H. G. Friesen, 1972. Studies of prolactin secretion in human pregnancy.Amer. J. Obstet. Gynecol., 113: 14–20.
Wolf, L. G., L. A. Falk, &F. Deinhardt, 1971. Oncogenicity of herpesvirus saimiri in marmoset monkeys.J. Nat. Cancer Inst., 47: 1145–1162.
Wood, J. M., H. P. Baum, R. A. Jobber, &D. Neisius, 1987. Sustained reduction in blood pressure during chronic administration of a renin inhibitor to normotensive marmoset.J. Cardiovasc. Pharmacol., 10: 96–98.
————,N. Gulati, J. B. Michel, &K. G. Hofbauer, 1986. Two-kidney, one clip renal hypertension in the marmoset.J. Hypertension, 4: 251–254.
Yoshida, T., K. Yokota, F. Cho, &S. Honjo, 1984. Circulating levels of gonadotropins and ovarian luteinizing hormone-resepter in female cynomolgus monkeys.Gunma Symposia on Endocrinol., 21: 107–125.
Author information
Authors and Affiliations
About this article
Cite this article
Moro, M., Torii, R., Koizumi, H. et al. Serum levels of prolactin during the ovarian cycle, pregnancy, and lactation in the common marmoset (Callithrix jacchus). Primates 36, 249–257 (1995). https://doi.org/10.1007/BF02381350
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02381350