, Volume 24, Issue 2, pp 260–265 | Cite as

Effects of stimulation of hypothalamic “feeding areas” on endocrines and metabolism in normal and diabetic monkeys

  • S. K. Garg
  • G. S. Chhina
  • Baldev Singh


Electrical stimulation of hypothalamic “feeding areas” (VMH & LHA) through stereotaxically implanted electrodes was carried out in normal and streptozotocinized diabetic conscious male rhesus monkeys. In normal monkeys, the VMH stimulation resulted in a significant decrease in serum insulin and blood glucose while opposite responses were observed following LHA stimulation. Serum growth hormone, FFA and plasma cortisol levels increased significantly on stimulation of LHA and VMH in normal animals. The pattern of blood glucose and serum growth hormone responses to stimulation of “feeding areas” was similar in normal and diabetic animals. The serum insulin, FFA and plasma cortisol were largely unaffected while growth hormone increased significantly by stimulation of these areas in diabetes. The present study indicates that the stimulation of “feeding areas” does not alter the diabetic syndrome significantly nor does diabetes prevent the changes in metabolism seen after stimulation of “feeding areas.”


Blood Glucose Growth Hormone Cortisol Level Rhesus Monkey Serum Insulin 
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Copyright information

© Japan Monkey Centre 1983

Authors and Affiliations

  • S. K. Garg
    • 1
  • G. S. Chhina
    • 1
  • Baldev Singh
    • 1
  1. 1.Department of BiologyGuru Nanak Dev UniversityAmritsarIndia

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