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Regulation of prostaglandin E2 synthesis by cyclooxygenase induction in osteoblast MC3T3-E1

  • 5. Prostaglandins In Bone Metabolism
  • Published:
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References

  1. Klein, D. C. and Raisz, L. G.: Prostaglandins: Stimulation of bone resorption in tissue culture. Endocrinology 86, 1436–1440, 1970.

    CAS  PubMed  Google Scholar 

  2. Yamamoto, S.: Enzymes in the arachidonic acid cascade. In: Prostaglandins and Related Compounds (C. Pace-Asciak and E. Granström, eds.), Elsevier, Amsterdam, pp. 171–202, 1983.

    Google Scholar 

  3. Kodama, H., Amagai, Y., Sudo, H., Kasai, S. and Yamamoto, S: Establishment of a clonal osteogenic cell line from newborn mouse calvaria. Jpn. J. Oral Biol. 23, 899–901, 1981.

    Google Scholar 

  4. Sudo, H., Kodama, H., Amagai, Y., Yamamoto, S. and Kasai, S.: In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J. Cell Biol. 96, 191–198, 1983.

    Article  CAS  PubMed  Google Scholar 

  5. Kumegawa, M., Hiramatsu, M., Hatakeyama, K., Yajima, T., Kodama, H., Osaki, T. and Kurisu, K.: Effect of epidermal growth factor on osteoblastic cells in vitro. Calcif. Tissue Int. 35, 542–548, 1983.

    CAS  PubMed  Google Scholar 

  6. Yokota, K., Kusaka, M., Oshima, T., Yamamoto, S., Kurihara, N., Yoshino, T. and Kumegawa, M.: Stimulation of prostaglandin E2 synthesis in cloned osteoblastic cells of mouse (MC3T3-E1) by epidermal growth factor. J. Biol. Chem. 261, 15410–15415, 1986.

    CAS  PubMed  Google Scholar 

  7. Sumitani, K., Kawata, T., Yoshimoto, T., Yamamoto, S. and Kumegawa, M.: Fatty acid cyclooxygenase activity stimulated by transforming growth factor-β in mouse osteoblastic cells (MC3T3-E1). Arch. Biochem. Biophys. 270, 588–595, 1989.

    Article  CAS  PubMed  Google Scholar 

  8. Kusaka, M., Oshima, T., Yokota, K., Yamamoto, S. and Kumegawa, M.: Possible induction of fatty acid cyclooxygenase in mouse osteoblastic cells (MC3T3-E1) by cAMP. Biochim. Biophys. Acta 972, 339–346, 1988.

    CAS  PubMed  Google Scholar 

  9. Yokoyama, C., Takai, T. and Tanabe, T.: Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence. FEBS Lett. 231, 347–351, 1988.

    Article  CAS  PubMed  Google Scholar 

  10. Hakeda, Y., Ikeda, E., Kurihara, N., Nakatani, Y., Maeda, N. and Kumegawa, M.: Induction of osteoblastic cell differentiation by forskolin. Stimulation of cyclic AMP production and alkaline phosphatase activity. Biochim. Biophys. Acta 838, 49–53, 1985.

    CAS  PubMed  Google Scholar 

  11. Hakeda, Y., Hotta, T., Kurihara, N., Ikeda, E., Maeda, N., Yagyu, Y. and Kumegawa, M.: Prostaglandin E1 and F stimulate differentiation and proliferation, respectively, of clonal osteoblastic MC3T3-E1 cells by different second messengers in vitro. Endocrinology 121, 1966–1974, 1987.

    CAS  PubMed  Google Scholar 

  12. Roesler, W. J., Vandenbark, G. R. and Hanson, R. W.: Cyclic AMP and the induction of eukaryotic gene transcription. J. Biol. Chem. 263, 9063–9066, 1988.

    CAS  PubMed  Google Scholar 

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Yamamoto, S., Oshima, T., Yoshimoto, T. et al. Regulation of prostaglandin E2 synthesis by cyclooxygenase induction in osteoblast MC3T3-E1. J Bone Miner Metab 9, 45–48 (1991). https://doi.org/10.1007/BF02377985

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  • DOI: https://doi.org/10.1007/BF02377985

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