Low cancer death rate in chronic dialysis patients with diabetes mellitus
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Little epidemiological data is available on the association between cancer and secondary hyperparathyroidism. We previously reported that the cancer death rate is significantly higher in chronic dialysis patients who usually have secondary hyperparathyroidism than that of the general population. In diabetic dialysis watients, prevalence of secondary hyperparathyroidism was reported to be less than non-diabetic patients, consequently less renal osteodystrophy. Therefore, we further analyzed whether the diabetic dialysis patients have less cancer death rate than that of the non-diabetic patients by using the Okinawa Dialysis Registry. From the annual report on the cancer death rate in the general population, we calculated the relative risk, observed/expected ratio, in sex and age-class adjusted. The relative risk of cancer death was 4.26 in non-diabetic and 1.64 in diabetic dialysis patients. Our results support the notion that there is a close relation between parathyroid hormone and neoplasia.
Key wordscancer death rate secondary hyperparathyroidism diabetes mellitus chronic dialysis
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