Abstract
We isolated cDNA fragments encoded in an X-chromosome specific YAC from the locus DXS995 by using direct cDNA selection method. Several of the selected cDNA fragments were identical to various exons of cyclophilin A gene. Hybridization of the selected cyclophilin cDNA fragments to the target YAC, presence of these sequences in an X-chromosome specific phage library and absence of a cross hybridizing fragment in a cell line (XL-45) that contains deletions of the interval Xq21, demonstrates that a cyclophilin like sequence is present in the human X-chromosome.
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Kandpal, G., Jacob, A.N.K. & Kandpal, R.P. A cyclophilin gene-like sequence maps to human X-chromosome. Somat Cell Mol Genet 22, 67–73 (1996). https://doi.org/10.1007/BF02374377
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DOI: https://doi.org/10.1007/BF02374377