Diabetologia

, Volume 38, Issue 1, pp 126–128 | Cite as

Further evidence for reduced beta2-adrenoceptor expression and modification of its density at a level beyond gene expression

  • P. Kotanko
  • O. Höglinger
  • A. Binder
  • F. Skrabal
Letters to the Editors

Keywords

Public Health Gene Expression Internal Medicine Human Physiology Metabolic Disease 

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References

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    Reynisdottir S, Wahrenberg H, Carlström K, Rössner S, Arner R (1994) Catecholamine resistance in fat cells of women with upper-body obesity due to decreased expression of beta2 adrenoceptors. Diabetologia 37: 428–435PubMedGoogle Scholar
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    Kobilka BK, Dixon RA, Frielle T et al. (1987) cDNA for the human β-2 adrenergic receptor: a protein with multiple membrane spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. Proc Natl Acad Sci USA 84: 46–50PubMedGoogle Scholar
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    Emorine LJ, Marullo S, Delavier-Klutchko C, Kaveri SV, Durieu-Trautmann O., Strosberg AD (1987) Structure of the gene for human β-2 adrenergic receptor: expression and promoter characterization. Proc Natl Acad Sci USA 84: 6995–6999PubMedGoogle Scholar
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    Rands E, Candelore MR, Cheung AH, Hill WS, Strader CD, Dixon RAF (1990) Mutational analysis of β-adrenergic receptor glycosylation. J Biol Chem 265: 10759–10764PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • P. Kotanko
    • 1
  • O. Höglinger
  • A. Binder
  • F. Skrabal
  1. 1.Department of Internal MedicineKrankenhaus Barmherzige BrüderGrazAustria

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