Theoretical analysis of the effects of diffusivity on pulmonary gas transport and mixing
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The effects of different tracer gas diffusivities upon pulmonary gas transport and mixing have been examined by means of a physico-mathematical lung model. Specifically, it is demonstrated how the expired alveolar plateau slope of a tracer gas gives an indication of the magnitude of the end expiratory concentration differences existing in the acinus. Further, by modifying the initial analysis slightly (to allow for a finite flux of gas across the alveolar wall) it has been indicated how more marked stratified inhomogeneities are associated with the transport of soluble rather than isoluble tracer gases.
KeywordsTheoretical Analysis Initial Analysis Concentration Difference Alveolar Wall Lung Model
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- 1.Chang, H.K. and L.E. Farhi. A mathematical analysis of gas transport in the lung.Respir. Physiol. 18:370–385, 1973.Google Scholar
- 5.Jones, T.J.Theoretical Analysis of Gas Transport and Transfer in Human Lungs. Ph.D. Thesis, University of Aston in Birmingham, Birmingham, England, 1977.Google Scholar
- 10.Sasaki, T. and L.E. Farhi. In:Symposium on Circulatory and Respiratory Mass Transport, a CIBA Foundation Symposium, edited by G.E.W. Wolstenholme and Julie Knight. London: Churchill, 1969.Google Scholar
- 11.Scrimshire, D.A. A revised model of gas transport in human lungs.Appl. Math. Modelling 3: 289–294, 1979.Google Scholar