Annals of Biomedical Engineering

, Volume 7, Issue 5–6, pp 375–386 | Cite as

Theoretical analysis of the effects of diffusivity on pulmonary gas transport and mixing

  • David A. Scrimshire
  • Robert J. Loughnane


The effects of different tracer gas diffusivities upon pulmonary gas transport and mixing have been examined by means of a physico-mathematical lung model. Specifically, it is demonstrated how the expired alveolar plateau slope of a tracer gas gives an indication of the magnitude of the end expiratory concentration differences existing in the acinus. Further, by modifying the initial analysis slightly (to allow for a finite flux of gas across the alveolar wall) it has been indicated how more marked stratified inhomogeneities are associated with the transport of soluble rather than isoluble tracer gases.


Theoretical Analysis Initial Analysis Concentration Difference Alveolar Wall Lung Model 
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Copyright information

© Pergamon Press Ltd. 1980

Authors and Affiliations

  • David A. Scrimshire
    • 1
  • Robert J. Loughnane
    • 1
  1. 1.Department of Production Technology and Production Management Biomedical Engineering SectionUniversity of Aston in BirminghamBirminghamEngland

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